Senior Market Access Manager
Johannesburg - South Africa
Job Summary
Do you have expertise in and passion for Market Access and creating value for our customers and patients If so AstraZeneca might be the one for you
ABOUT ASTRAZENECA
AstraZeneca is a global global science-led patient-focused Biopharmaceutical business that focuses on the discovery development and commercialization of prescription medicines for some of the worlds most serious diseases. But we are more than one of the worlds leading pharmaceutical companies. At AstraZeneca we are dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There is no better place to make a difference to medicine patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning growth and development. Our strategic priorities reflect how we are working to deliver our strategy and achieve our a workforce we are the catalyst for our values: we are entrepreneurial; we do the right thing; we play to win; we put patients first and we follow the science. As a company we appreciate and take great pride in each team member where every person is brought together through shared values that underpins a shared purpose. There is no better place to feel inspired and energised. Answer unmet medical needs by pioneering the next wave of science focusing on outcomes and crafting the patient ecosystem.
At AstraZeneca were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. Join the fastest-growing pharmaceutical in our markets set up to fuel further growth. Be part of our shared ambition and pride: our strong heritage our turnaround story and early investment and commitment in international markets. Theres no better place to feel inspired and energized.
ABOUT THE MARKET ACCESS TEAM
You will join a highperforming Market Access team that thrives at the edge of whats possiblediverse in backgrounds united by purpose and energized by solving hard problems in unconventional ways. On Monday you might whiteboard a fresh payer narrative with a health economist and a clinician; by Wednesday youre pressuretesting a contracting idea over coffee with a policy lead who challenges your assumptions; on Friday youre celebrating a milestone because a bold databacked approach unlocked access faster for patients who cant wait. Were driven and accountable curiosity in our debates in everything we do. If youre solutionoriented resilient when the path isnt obvious and excited to think differently to cocreate with stakeholders youll feel at home here and youll see your impact quickly in Rare Diseases and Oncology.
What You will do
You will be a critical player in the success of our Oncology and Rare Diseases portfolio by translating scientific leadership into real-world access for patients with lifethreatening serious diseases. You will shape and execute strategic medical imperatives across the asset lifecyclebuilding the value story early informing evidence generation and ensuring launch and postlaunch excellence. Day to day you will engage and cocreate with medical experts diagnostic specialists payers and patient advocacy groups to identify barriers across the patient journey promote earlier diagnosis and design pragmatic solutions that improve quality of care and speed timetoaccess. You will develop a deep scientific and medical understanding of the disease landscape (including diagnostics and treatment pathways) synthesize insights from clinics and systems and convert them into compelling payer strategies HTA narratives and contracting options. You will partner closely with Medical HEOR Policy and Commercial to generate and translate evidenceclinical RWE and economicinto clear credible value communication and negotiation readiness. You will track and shape the external environment anticipating policy shifts budget dynamics and stakeholder needs while measuring impact through welldefined KPIs and continuously optimizing our approach. Throughout you will bring a solutionoriented mindset and resilient execution fostering mutually beneficial partnerships that unlock sustainable access for patients who need it most.
Job Description:
Access Strategy: Lead endtoend Funder and HTA strategy from early launch prep readiness and evidence shaping to launch and inline optimization; define clear access objectives and KPIs per therapeutic area.
Evidence Planning: Partner with HEOR/Medical to identify evidence gaps and inform clinical RWE and economic model needs aligned to payer questions.
Value Proposition: Craft and continually refine value stories core value dossiers and objection handlers amongst others
Scenario Planning: Pricing Business Cases Budget Impact against local policy and affordability dynamics.
Key Responsibilities:
External Engagement and Internal Cross Functional Collaboration.
Stakeholder CoCreation: Build trusted relationships with payers HTA committees policy makers clinicians diagnostic specialists patient advocacy groups and codesign pragmatic access pathways.
Negotiations & Submissions: Lead or coordinate Dossier and/or HTA/payer submissions price/access negotiations; ensure highquality compliant accurate materials and rapid turnaround on queries.
Policy Shaping: Monitor and contribute to policy developments (reimbursement frameworks formulary processes health technology prioritization) providing credible input that advances patient access.
Key Responsibilities Pricing Policy Shaping & Governance
Pricing Strategy: Recommend list/net pricing tender approaches and affordability programs (PAP) aligned with global and local policies
Compliance: Ensure adherence to AZ policies and governance; maintain robust documentation audit readiness and nominated signatory alignment for access materials where applicable.
Key Responsibilities CrossFunctional Leadership
Launch Excellence: Orchestrate market readiness stakeholder mapping negotiation playbooks and postlaunch performance tracking; drive course corrections based on KPIs.
Insight to Action: Systematically capture Funder and system insights and convert them into strategy updates evidence requests and field guidance.
Team Enablement: Coach commercial field colleagues on Funder value messaging economic model use and objection handling; elevate access fluency across the organization.
Responsibility to promptly collect and report any adverse events and product quality complaints received from any source. All such cases must be documented accurately and submitted to the designated department within one business day of becoming aware of the information ensuring compliance with company policies and applicable regulatory requirements.
Responsibility to complete Adverse Event training during initial onboarding and then annually thereafter.
If this sounds appealing please read on to understand the experience and skills were looking for
ESSENTIAL SKILLS AND EXPERIENCE REQUIRED
Completed Bachelors Degree in Life Sciences pharmacy health economics public health or a business field
Management and Healthcare Experience: Preferably at least 5 years in Commercial Market Access/HEOR/ or Pricing & Reimbursement in Pharmaceutical Sector or consulting with a strong record in Oncology and/or Rare Diseases.
HTA & Payer Submissions: Endtoend experience leading HTA/payer submissions including evidence alignment dossier development stakeholder Q&A and panel preparation.
Pricing: Proven capability in pricing strategy budget impact modeling and innovative agreements
Health Economics & RWE: Working proficiency with costeffectiveness models BIAs sensitivity analyses and translating RWE into payerrelevant value.
Stakeholder Engagement: Track record building trusted relationships with payers policy makers clinicians diagnostic specialists and patient organizations; skilled in cocreation and negotiation.
Policy & System Knowledge: Understanding of SA reimbursement pathways and evolving policy landscape.
CrossFunctional Leadership: Ability to align Medical HEOR Commercial Regulatory Policy and Finance; experience orchestrating launch excellence and postlaunch optimization.
Communication & Influence: Exceptional ability to simplify complexity craft compelling value stories and influence senior stakeholders; strong written materials (dossiers objection handlers slide narratives).
Analytical & Strategic Agility: Structured problemsolver with data literacy and comfort with ambiguity; adept at scenario planning and translating insights into action.
Governance & Compliance: Knowledge of promotional and accessrelated compliance requirements documentation standards and audit readiness; alignment with AZ policies and local codes.
People & Team Skills: Collaborative solutionoriented mindset with resilience; mentoring/coaching experience a plus.
Digital / AI Fluency: openness to new digital platforms.
Why AstraZeneca
We are proud to have achieved Top Employer certification in South Africa Kenya and Nigeria for 2026. This distinction is a confirmation of our commitment and ability to sustain people partnerships and employee engagement and foster an innovative workplace environment.
At AstraZeneca were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. Theres no better place to make a difference to medicine patients and society. An inclusive culture that champions diversity and collaboration and always committed to lifelong learning growth and development. Were on an exciting journey to pioneer the future of healthcare. Join the fastest-growing pharmaceutical in our markets set up to fuel further growth. Be part of our shared ambition and pride: our strong heritage our turnaround story and early investment and commitment in international markets. Theres no better place to feel inspired and energized.
SO WHATS NEXT
Are you already imagining yourself joining our team Good because we cant wait to hear from you!
Click the link to apply no later than 12 May 2026 and well be in touch as soon as we can.
WHERE CAN I FIND OUT MORE
Our social media Follow AstraZeneca on LinkedIn AstraZeneca on Facebook Date: 12/05/2026
Date Posted
05-May-2026Closing Date
12-May-2026AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.
Required Experience:
Manager
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more