DescriptionPosition Details
Department of Inflammation and Ageing School of Infection Inflammation and Immunology College of Medicine and Health
Location: University of Birmingham Edgbaston Birmingham UK
Full time starting salary is normally in the range 36130 to 45413 with potential progression once in post to 48149
Grade: 7
Full Time Fixed Term contract up to August 2026
Closing date: 6th August 2025
Background
We are seeking a talented and motivated post-doctoral researcher to join Rheumatology Research Group. The Research Fellow will be supervised by Dr John Reynolds and Dr Jason Turner within the Department of Inflammation and Ageing at the University of Birmingham. The successful candidate will work to deliver high level computational analysis of immune cell subsets in patients with cutaneous lupus erythematosus (CLE).
The researcher will work to deliver a specific project to understand the biology of immune cells especially T cells in the skin of patients with (CLE) using single-cell transcriptomics.
The successful candidate will work in close association with teams consisting of laboratory-based and clinical researchers to deliver the with analysis of transcriptomic data is essential.
Role Summary
- Work withinthe Department of Inflammation and Ageing
- Operate within area of specialism
- Analyse and interpret research findings and support their publication
- Contribute to generating external funding
- Develop and make contributions to knowledge transfer enterprise business engagement or similar activities at Department/School level or further within the University
Main Duties
Theresponsibilities may include some but not all of the responsibilities outlined below.
- Design and conduct bioinformatic data analysis pipelines under the guidance of the research supervisor to test the project hypotheses and complete project aims
- Develop research objectives which may include proposals for further research with assistance of a mentor if required
- Contribute to writing bids for research funding that enhance the work of the department
- Analyse and interpret data
- Apply knowledge in a way which develops new intellectual understanding
- Disseminate research findings for publication research seminars etc
- Supervise students on research-related work and provide guidance to PhD students where appropriate to the discipline
- Contribute to developing new computational models techniques and methods
- Undertake management/administration arising from research
- Contributeto Departmental/School research-related activities and research-related administration
- Contribute to enterprise business development and/or public engagement activities of manifest benefit to the College and the University often under supervision of a project leader
- Collect research data; this may be through a variety of research methods such as scientific experimentation literature reviews and research interviews
- Present research outputs including drafting academic publications or parts thereof for example at seminars and as posters
- Provide guidance as required to support staff and any students who may be assisting with the research
- Deal with problems that may affect the achievement of research objectives and deadlines
- Promotes equality and values diversity acting as a role model and fostering an inclusive working culture
Person Specification
- A First degree which should have links with informatics and science e.g. biological biomedical natural sciences computing informatics and computer science. A PhD(or near to completion) or equivalent experience in Biological or Biomedical sciences Immunology or Bioinformatics
- High level analytical capability
- Broad understanding of next generation sequencing (NGS) technologies and demonstration of proven experience in analysis of bulk and single cell transcriptomic data would be an advantage
- Ability to communicate complex information clearly
- Evidence of an ability to write to a standard required for research reports/publications
- Effective interpersonal and communication skills (e.g. ability to interact with project partners and explain complex ideas to non-bioinformaticians in an understandable way)
- Work in a heterogeneous environment of Clinicians Biologists and Bioinformaticians
- Fluency in relevant models techniques or methods and ability to contribute to developing new ones
- Demonstrate knowledge of bioinformatics resources such as annotation tools and databases
- Demonstrate proficiency in R/BioConductor and High Level (e.g. python) programming languages Databases (SQL) development and maintaining code repositories (version control)
- Demonstrate Linux expertise including file systems shell hardware/software monitoring etc
- Demonstrate an understanding of practical applications of bioinformatics for immunological or inflammation research
- Ability to assess resource requirements and use resources effectively
- Learn and keep abreast of latest technological methodological and software developments
- Understanding of and ability to contribute to broader management/administration processes
- Contribute to the planning and organising of the research programme and/or specific research project
- Co-ordinate own work with others to avoid conflict or duplication of effort
- Knowledge of the protected characteristics of the Equality Act 2010 and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly
Further particulars can be foundhere
Informal enquiries to Lisa Powell email:
We believe there is no such thing as a typical member of University of Birmingham staff and that diversity in its many forms is a strength that underpins the exchange of ideas innovation and debate at the heart of University life. We are committed to proactively addressing the barriers experienced by some groups in our community and are proud to hold Athena SWAN Race Equality Charter and Disability Confident accreditations. We have an Equality Diversity and Inclusion Centre that focuses on continuously improving the University as a fair and inclusive place to work where everyone has the opportunity to succeed. We are also committed to sustainability which is a key part of our strategy. You can find out more about our work to create a fairer university for everyoneon our website.