Research Fellow
Research Fellow
Posted on :
09-04-2025
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1 Vacancy
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Job Description
Massachusetts General Hospital is an Equal Opportunity Employer. By embracing diverse skills perspectives and ideas we choose to lead. Applications fromprotected veterans and individuals with disabilities are strongly encouraged.Postdoctoral Fellow Positions available for computational biologists or bioinformatic specialists at the Postdoctoral Fellow or Staff Scientist level in the Center for Human Genetic Research at Massachusetts General Hospital and Harvard Medical School as well as the Program in Medical and Population Genetics at the Broad Institute. Projects involve functional genomic studies of autism spectrum disorder (ASD) genes including analysis of RNAseq and ChIPseq data in iPSderived neuronal cells altered by genome editing methods and extensive functional genomic studies of chromosomal abnormalities in human disease. Positions will be shared between the laboratories of Dr. James Gusella Director of the Center for Human Genetic Research and Dr. Michael Talkowski Assistant Professor of Neurology (Genetics) and Director of the Genomics and Technology Core.Candidates will have the opportunity to work in a unique translational genomics environment that will integrate computational genomics technology development and an advanced molecular genomics laboratory and will have significant independence with appointments to MGH HMS and the Broad Institute and will interact with collaborators at all three institutions. The ideal candidate will have an interdisciplinary background in bioinformatics & computational biology advanced expertise in the analysis and interpretation of nextgeneration sequencing data focusing on RNAseq and CHiPseq and its integration with other omics data sources or demonstrated expertise in human genetics and bioinformatics; good programming skills; and advanced knowledge of statistical methods.Required Skills A Ph.D. in human genetics quantitative genetics computational biology bioinformatics computer science or mathematics. A truly exceptional candidate with a Masters degree in these fields may be considered. No candidate without advanced training in bioinformatics or computational biology will be reviewed. Ability to program in Python Perl and R. Familiarity with Unix systems and parallel computing. Familiarity with RNA and DNA sequencing alignment tools (e.g. Tophat GSNAP BWA) RNAseq analysis tools (e.g. cufflinks/cuffdiff DESeq EdgeR) and CHiPseq analysis tools (e.g. MACS SPP) All candidates should provide a cover letter and academic curriculum vitae or resume and if selected for an interview will be required to provide three letters of reference from academic or industry supervisors.Address applications and inquiries to:Michael E. Talkowski Ph.D.Assistant Professor of Neurology (Genetics)Director Genomics and Technology CoreCenter for Human Genetic ResearchMassachusetts General Hospital and HarvardMedicalSchoolAssociate Member Broad Institute of M.I.T. and : Ms. Dorianne Griffin F. Gusella Ph.D.DirectorMGH Center for Human Genetic ResearchBullard Professor NeurogeneticsDepartment of Genetics Harvard Medical SchoolAssociate Member Broad Institute of M.I.T. and : Ms. Pamela Ricevuto
Employment Type
Full-Time
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