Senior CMC Program Manager

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.

• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview:

We are seeking a Senior Program Manager CMC to lead and coordinate cross-functional Chemistry Manufacturing and Controls (CMC) activities within a cell therapy development and manufacturing environment. The Senior Program Manager CMC will drive planning execution and integration across manufacturing analytical quality regulatory and supply chain functions to support clinical development and commercialization goals. This role serves as a strategic partner across technical and operational teams ensuring alignment proactive risk management and readiness for key milestones including regulatory submissions and commercial manufacturing.

Reports to: Senior Director
Location: 13203 Murphy Road Suite 100 Stafford TX 77477

Basic Qualifications:

• Masters degree in life sciences medicine immunology oncology pharmacy health sciences or a related field

• 6 years of experience in CMC program/project management or complex project leadership within biotechnology pharmaceutical or oncology-focused clinical development environments

• Demonstrated experience leading cross-functional CMC activities including manufacturing quality analytical and regulatory operations

• Academic or industry experience in cell and gene therapy immunology/oncology or bioprocessing/manufacturing sciences

• Proven leadership stakeholder management and organizational skills with the ability to manage competing priorities in fast-paced environments

Preferred Qualifications:

• PhD in life sciences medicine immunology oncology pharmacy health sciences or a related field

• Experience supporting late-stage CMC programs in immunology oncology or cell and gene therapy

• Proven experience managing complex programs and critical paths across multiple technical and operational functions

• Proficiency with project management tools dashboards and reporting systems in regulated environments

• Advanced ability to identify risks drive decision-making and implement process improvements across cross-functional teams

• Experience coordinating external vendors CMOs CDMOs or consulting partners

• Strong communication and presentation skills with experience supporting senior leadership discussions and strategic planning

In this role you will:

• Develop and maintain CMC program plans timelines risk registers trackers and reporting tools to support integrated program execution

• Manage CMC deliverables milestones and critical paths while ensuring alignment with overarching development program timelines

• Lead and facilitate cross-functional CMC meetings including agenda development documentation action tracking and follow-up activities

• Drive collaboration across Manufacturing Process Development Analytical Development Quality Regulatory Supply Chain and Patient Operations teams

• Coordinate and oversee activities with external vendors contractors CMOs and CDMOs

• Support strategic planning governance and decision-making activities with department leaders and senior management

• Contribute to continuous improvement of CMC program management tools processes onboarding and operational best practices

What do we offer

At Immatics we believe in investing in our teams health safety and well-being. Heres what you can expect if you join Immatics

Comprehensive Benefits:

• Competitive rates for Health Dental and Vision Insurance

• 4 weeks of vacation granted up front each year and prorated for first and last year of employment.

• 12 company paid holidays

• 7 days of sick time

• 100% employer-paid life insuranceup to at 1x annual salary up to one hundred thousand dollars

• 100% employer-paid short- and long-Term disability coverage

• 401(k) with immediate eligibilityand company match

  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment 4% for years 2-3 of employment and up to 5% of your salary from the fourth year onward of continued employment.

• Partially paid parental leavefor eligible employees.

• Additional voluntary employee-paid benefits and services including accident hospital indemnity and critical illness insurance as well as identity theft protection and pet insurance.

Equal Employment Opportunity

We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard torace color religion sex (including pregnancy childbirth or related medical conditions) sexualorientation gender identity or expression national origin ancestry age marital status disability geneticinformation veteran status or any other status protected by applicable law.

Reasonable Accommodations

We are committed to providing reasonable accommodations to individuals with disabilities and to applicants withsincerely heldreligious beliefs practices or observances. If you require assistance or accommodation during the application or interview process please contact us at.

Work Authorization

Applicants mustbe authorized towork in the United States without the need for current or future sponsorship. Visa sponsorships may beavailablefor certain roles.

Pre-Employment Requirements

Employment is contingent upon successful completion of a background check referencechecksand pre-employment drug screening wherepermittedby applicable law. For certain rolesadditionalscreenings such as a credit check or motor vehicle record review may berequired where job-related and consistent with business necessity.