Director of Anti-infective Pharmacology will lead and manage a team responsible for designing executing and interpreting preclinical pharmacology studies to support the development of novel anti-infective therapeutics. This individual will play a key role in advancing our pipeline of anti-infective compounds by providing scientific expertise strategic guidance and leadership to drive programs from early discovery through preclinical development. This position is an office/lab -based position located in San Diego CA.

Essential Duties and Responsibilities

1. Leadership and Team Management:

o Lead and mentor a team of scientists to execute preclinical pharmacology and toxicology studies.

o Foster a collaborative and innovative culture within the team to achieve program goals.

o Provide scientific and strategic guidance to team members and contribute to their professional development.

1. Preclinical and Clinical Pharmacology:

o Develop and implement strategies to support the advancement of anti-infective drug candidates in the preclinical and clinical setting.

o Design and oversee in vitro and in vivo pharmacology studies to characterize the pharmacokinetic and pharmacodynamic properties of lead compounds and development candidates.

o Understanding of and previous experience conducting and evaluating population pharmacokinetic analyses

o Evaluate emerging scientific trends and technologies to enhance team capabilities.

1. Experimental Design and Execution:

o Design and oversee the execution of preclinical studies to evaluate the pharmacokinetics efficacy and safety of anti-infective compounds.

o Collaborate with cross-functional teams including medicinal chemistry biology and translational research to integrate pharmacology data into drug discovery and development efforts.

1. Data Analysis and Interpretation:

o Analyze and interpret preclinical and clinical pharmacology data to guide decision-making and optimize compound selection and progression.

o Generate high-quality scientific reports presentations and publications to communicate study findings internally and externally.

1. Cross-Functional Collaboration:

o Collaborate closely with other functional areas including medicinal chemistry pharmacokinetics toxicology and clinical development to drive project progression and decision-making.

o Contribute to cross-functional project teams and provide pharmacology expertise to support overall drug development strategies.

1. External Engagement:

o Represent the company externally by presenting at scientific conferences participating in advisory boards and fostering collaborations with academic and industry partners.

o Stay abreast of advancements in anti-infective pharmacology and contribute to scientific discourse through publications and presentations.

Qualifications

• The position requires a Pharm.D. Ph.D. or equivalent degree in pharmacology microbiology or related field with a minimum of 10 years of industry or government experience in anti-infective drug discovery and development; or equivalent combination of education and experience.
• Demonstrated leadership experience in managing scientific teams and leading discovery and development programs.
• Expertise in designing and executing in vitro and in vivo pharmacology studies to evaluate anti-infective compounds.
• Strong understanding of infectious diseases pharmacokinetics pharmacodynamics and regulatory requirements.
• Experience with a variety of pharmacology techniques and assays including microbiological assays animal models of infection PK-PD and population pharmacokinetic analyses.
• Excellent communication and presentation skills with the ability to effectively communicate complex scientific concepts to diverse audiences.
• Proven track record of productivity innovation and scientific contributions demonstrated by peer-reviewed publications and presentations at scientific conferences.
• Ability to thrive in a fast-paced collaborative and dynamic work environment.

Additional Information

The base salary range for this full-time position is $210000 - $250000. Individual pay is determined by several factors which include but are not limited to: job-related skills experience and relevant education or training. The range does not include the comprehensive benefits bonus long-term incentive applicable allowances or any additional compensation that may be associated with this role.

Shionogi Inc. is an equal opportunity employer supporting individuals with disabilities and veterans. All qualified applicants will receive equal consideration for employment opportunities based on valid job requirements without regard to race color religion sex (including pregnancy) marital status national origin age ancestry citizenship disability genetic information status as a disabled veteran a recently separated veteran Active Duty Wartime or Campaign Badge Veterans and Armed Forces Service Medal Veterans or any other characteristic protected by applicable law. It is the policy of Shionogi Inc. to undertake affirmative action for protected veterans and individuals with disabilities in compliance with all federal state and local requirements to recruit a diverse pool of protected veteran and individuals with disabilities applicants and to ensure that our employment practices are in fact non-discriminatory.

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