Associate Scientist In Vitro Neurobiology

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year.

Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Associate Scientist- In Vitro Neurobiology

What you will do

Lets do this. Lets change the world. Amgens cardiometabolic team is an innovative target discovery and translational research unit with a focus on identifying novel targets for development of game-changing therapies for patients with obesity and associated cardiometabolic diseases. We employ advanced computational biology state-of-the-art discovery screening technologies genetics and human-centric cell systems to dissect pathophysiology and identify novel drug targets.

This laboratory-based position will focus on cell culture support for the development of large-scale qualitative and quantitative functional genomics screens utilizing human derived central nervous system (CNS) models. There is an overarching aim to characterize genes and genetic regulatory circuits involved in the control of cellular metabolism and advance discovery projects by performing in vitro experiments under partial supervision.

Key Responsibilities:

• Work in an in vitro setting using aseptic technique passaging expansion cryopreservation assessment of cell-line quality and cell characterization
• Maintain mammalian cell cultures derived from iPSC and/or primary neuronal or glial models
• Utilize functional cell-based assays and support in the development of immunoassays (western blot ELISA flow cytometry immunofluorescence staining) fluorescent microscopy and other imaging methods
• Operate and maintain standard lab equipment
• Document experimental plans and procedures timely with attention to detail
• Exhibit self-motivation and proactive attitude in designing and conducting experiments using state-of-the-art technologies
• With some supervision plan conduct or monitor experiments record and organize data analyze results troubleshoot and generate robust and reliable data

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a team player with these qualifications.

Basic Qualifications:

Masters degree and 1 year of related scientific experience

OR

Bachelors degree and 3 years of related scientific experience

Preferred Qualifications:

• At least 3 years of mammalian cell culturing experience
• Demonstrated experience using assay technologies (e.g. luminescence fluorescence TR-FRET AlphaLISA or high-content systems).
• Experience performing molecular biology experiments (such as RNA DNA extraction qPCR cloning CRISPR/Cas9-based genome editing) or performing antibody-based experiments (flow cytometry ELISA immunofluorescence imaging and western blot).
• Hands-on experience in handling samples in 96-well format is preferred
• Familiarity with Metabolic Disease Pathophysiology
• Strong organizational analytical and problem-solving skills
• Proficiency in GraphPad Prism Microsoft Word Excel and PowerPoint

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range