Research Fellow Department of Cancer and Genomic Sciences 107030 Grade 7

Position Details

Department of Cancer and Genomic Sciences School of Medical Sciences College of Medicine and Health

Location: University of Birmingham Edgbaston Birmingham UK

Full time starting salary is normally in the range 36636 to 46049 with potential progression once in post to 48822

Grade: 7

Full Time Fixed Term contract up to February 2031

Closing date: 10th March 2026

Background

To create and contribute to the creation of knowledge by undertaking a specified range ofactivities within an established research programme and/or specific research project.

This BBSRC (sLoLa) - funded post is established to study the semantic rules of developmental gene expression control. The post holder will be part of a multi-disciplinary consortium team (6 institutions in the UK) and work within the Department of Cancer and Genomic Sciences. Their main role will beto apply and develop new methods for precise genome manipulation to createtransgenic reporter models for asking questions about transcriptional regulation mechanisms of developmental gene expression.They will apply molecular phenotyping approaches such as high resolution genomics technologies in zebrafish embryo models.They will perform and develop cell resolution genomics assays (e.g. CAGE-seq and ATAC-seq) for analysing gene expression and gene regulatory element dynamics. They lead the Birmingham subteam including supervision of PhD student(s) and will work in close collaboration with experts at Edinburg University Imperial Manchester University and other partners in computational biology genome editing and genome synthesis post is available for 3 years in the first instance.

Role Summary

• Work within specified research grants and projects and contribute to writing bids

• Operate within area of functional genomics and developmental genetics

• Analyse and interpret research findings and results by embryo phenotyping by genomics and imaging tools publish high quality new results in peer reviewed journals

• Contribute to generating funding for further research in the area

• Contribute to licensing or spin out deals with demonstrated commercial success (such as revenues asset or company sales IP generated) and/or public understanding of the discipline or similar

Main Duties

The responsibilities may include some but not all of the responsibilities outlined below.

• Develop research objectives and proposals for own or joint research with assistance of a mentor if required
• Contribute to writing bids for research funding
• Analyse and interpret genomics embryo phenotyping and developmental genetic data
• Apply knowledge in a way which develops new intellectual understanding of transcription control
• Disseminate research findings for peer reviewed publication research seminars conferences and consortium meetings
• Supervise junior colleagues including PhD students on wet lab research and provide guidance where appropriate to the developmental genetics functional genomics
• Develop new models techniques and methods in genome editing and manipulation in vivo phenotyping
• Design subprojects and associated experiments develop new research studies and develop new projects within the research topic
• Undertake management/administration arising from research within the consortium and the wider research team and lead the subgroup working within the project
• Contribute to Departmental/School research-related activities and research-related administration
• Contribute to enterprise business development and/or public engagement activities of manifest benefit to the College and the University often under supervision of a project leader
• Collect research data; this may be through a variety of research methods such as scientific experimentation literature reviews
• Present research outputs including drafting academic publications or parts thereof for example at seminars and as posters
• Provide guidance as required to support staff and lead the work of students who may be assisting with the research
• Deal with problems that may affect the achievement of research objectives and deadlines
• Promotes equality and values diversity acting as a role model and fostering an inclusive working culture.

Person Specification

• First degree in biology or related subject and normally a PhD in biomedical research area or equivalent qualifications
• High level analytical capability
• Ability to communicate complex information clearly
• Fluency in embryo model (preferably zebrafish) associated genome manipulation techniques and ability to contribute to developing new ones including base and prime editing site specific recombination technologies
• Fluency in genetic manipulation tools applied in developmental genetics
• Ability to work with complex in vivo models (e.g. zebrafish embryos)
• Practical experience with molecular phenotyping by single cell and bulk genomics library preparation sequencing and experience with NGS data analysis
• Ability to assess resource requirements and use resources effectively
• Evidence of researcher capabilities in the form of major contributions (e.g first author) to peer reviewed publication(s)
• Understanding of and ability to contribute to broader management/administration processes
• Contribute to the planning and or leading and organising of the elements of the research programme and/or specific research project
• Co-ordinate own work with others to avoid conflict or duplication of effort
• Knowledge of the protected characteristics of the Equality Act 2010 and how to actively ensure in day to day activity in own area that those with protected characteristics are treated equally and fairly

Further particulars can be foundhere

Informal enquiries to Ferenc Mueller email:

Use of AI in applications:We want to understand your genuine interest in the role and for the written elements of your application to accurately reflect your own communication style. Applications that rely too heavily on AI tools can appear generic and lack the detail we need to assess your skills and experience. Such applications will unlikely be progressed to interview.

We believe there is no such thing as a typical member of University of Birmingham staff and that diversity in its many forms is a strength that underpins the exchange of ideas innovation and debate at the heart of University life. We are committed to proactively addressing the barriers experienced by some groups in our community and are proud to hold Athena SWAN Race Equality Charter and Disability Confident accreditations. We have an Equality Diversity and Inclusion Centre that focuses on continuously improving the University as a fair and inclusive place to work where everyone has the opportunity to succeed. We are also committed to sustainability which is a key part of our strategy. You can find out more about our work to create a fairer university for everyoneon our website.