Executive Director, Global Medical Affairs, GI

About Summit

Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life increasing potential duration of life and resolving serious unmet medical needs. At Summit we believe in building a team of world class professionals who are passionate about this mission and it is our people who drive this mission to reality. Summits core values include integrity passion for excellence purposeful urgency collaboration and our commitment to people. Our employees are truly the heart and soul of our culture and they are invaluable in shaping our journey toward excellence.

Summits team is inspired to touch and help change lives through Summits clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies including:

Non-small Cell Lung Cancer (NSCLC)

• HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI.

• HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC.

Colorectal Cancer (CRC)

• HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy.

Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than Chinas National Medical Products Administration (NMPA). Summit is headquartered in Miami Florida and has additional offices in California New Jersey the UK and Ireland.

Overview of Role:

The Executive Director Medical Affairs GI is a key leader and a subject matter expert responsible for shaping and executing the medical affairs strategy in GI cancers. This role oversees the development and implementation of medical affairs plans for lung-related indications including launch excellence for multiple indications lifecycle management and scientific engagement. The Executive Director will collaborate within the medical affairs department and cross-functionally with Clinical Development Regulatory Affairs Commercial and Market Access teams to ensure effective compliant and impactful disseminations of data education on disease and therapeutic information and interactions with healthcare professionals key opinion leaders and decision makers. Recent hands-on experience in GI cancers either in clinical practice or within pharmaceutical companies is essential.

Role and Responsibilities:

• Strategic Leadership
  • Develop and lead the US medical affairs strategy for GI cancers ensuring alignment with global medical clinical and commercialization objectives.
  • Oversee the design execution and reporting of medical activities supporting the launch and lifecycle management
  • Foster a culture of high performance collaboration skills development and scientific excellence across the medical affairs team.
• Team Leadership
  • Lead a high-performance matrixed team grounded in scientific rigor and integrity.
  • Mentor coach and develop others ensuring effective coverage and execution of medical initiatives.
• Scientific Engagement & Insight Generation
  • Establish and maintain relationships with KOLs HCPs and other external stakeholders to support scientific exchange and gather actionable insights.
  • Ensure effective communication of scientific data and information to external stakeholders representing Summit Therapeutics at scientific conferences meetings and other events.
  • Oversee the development and execution of prelaunch medical education programs strategic publications and data generation initiatives.
• Cross-functional Collaboration
  • Collaborate with Clinical Development Regulatory Commercial and other internal stakeholders to ensure strategic integration and alignment of medical activities.
• Compliance & Reporting
  • Ensure all medical affairs activities comply with regulatory and company policies.
  • Monitor and report on activities performance metrics and outcomes to senior leadership.
  • Participate in the development and adherence to departmental SOPs and ensure all activities are legally compliant and conducted according to company standards.
• All other duties as assigned

Experience Education and Specialized Knowledge and Skills:

Education

• Advanced scientific degree (MD PharmD PhD) required.

Experience

• Minimum of 12 years progressive Medical Affairs or related experience with at least 5 years in a leadership role.
• Significant recent experience in GI cancers either in clinical practice or within pharmaceutical/biotech companies is required.
• Proven track record of supporting product launches building and optimizing medical affairs teams and managing through leaders.
• Experience in a fast-paced evolving environment preferred.

Skills & Abilities

• Excellent leadership communication and stakeholder management skills.
• Strong analytical and strategic thinking abilities.
• Demonstrates resilience composure and effective decision-making in a dynamic and challenging environment.
• Ability to thrive in a matrixed cross-functional environment.
• Demonstrated ability to motivate develop and retain high-performing teams.
• Willingness to travel up to 40% as needed.

Additional Requirements

• Proficient user of standard MS Office suite (Word Excel) experience using electronic document management systems and document review tools.
• Must be able to effectively multi-task and manage time-sensitive and highly confidential documents.
• Work in a fast-paced demanding and collaborative environment.

The pay range for this role is $231000-$289000 annually. Actual compensation packages are based on several factors that are unique to each candidate including but not limited to skill set depth of experience certifications and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus stock benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summits Talent Acquisition team at to obtain prior written authorization before referring any candidates to Summit.