Technical Officer, Single Domain Antibodies

Discover the possible

Anything is possible at the National Research Council (NRC)recently named one of Canadas 2025 Top Employers for Young People a 2025 Top Employer in the National Capital Region and Forbes Canadas Best Employers!

As Canadas leading research and technology organization our world-renowned research pushes the boundaries of science and engineering to make the impossible possible. Every day we explore new ideas through innovative research and help companies discover possibilities that impact Canadas future and the world.

At the NRC youll also discover new possibilities. Our supportive workplace fosters a culture of creativity welcoming fresh perspectives and innovation at all levels. We value teamwork. Youll collaborate across multiple fields and with the brightest minds to find creative solutions. Most importantly youll discover whats possible within you as you grow make valuable contributions and progress in your professional journey. From ground-breaking discoveries to a life-changing career discover your possible at the NRC.

The Role

We are looking for a Technical Officer to support the Single Domain Antibodies team in our Human Health Therapeutics Research Centre. The incumbent would be someone who shares our core values of Integrity Excellence Respect and Creativity.

A typical day for the successful candidate will involve planning executing and analyzing data from a very diverse array of laboratory experiments used to isolate produce and characterize antibody-based samples (e.g. recombinant protein production antibody library generation and screening antibody purification and characterization). This day may also include training in one or several different techniques - as well as helping to train other colleagues assisting in administrative and support roles such as purchasing of reagents/supplies preparing scientific reports assisting in the development of new assays attending internal and external meetings writing standard operating procedures (SOPs) documenting experiments in laboratory notebooks general maintenance of equipment and laboratory facilities and presenting data at internal meetings. You will interact with and have the opportunity to learn from a diverse array of teams within the NRC community that have different expertise as well as many Canadian industrial (Biotech/Pharma) and academic partners.

This Technical Officer position would appeal to someone who is interested in the biology of disease and eager to learn how antibody-based therapeutic drugs are isolated characterized and developed to treat human diseases such as cancer.

The position would also interest someone who is flexible and has a passion for working hands-on in a laboratory setting learning new techniques helping to find solutions to challenging scientific problems and interacting with other scientists with diverse backgrounds.

Screening Criteria

Applicants must demonstrate within the content of their application that they meet the following screening criteria in order to be given further consideration as candidates:

Education

College diploma in biochemistry microbiology molecular biology biotechnology or a related field.

For information oncertificates and diplomas issued abroad please see Degree equivalency

Experience

• Experience conducting experiments in a molecular biology lab using techniques such as the isolation of RNA cDNA synthesis PCR RT-PCR cloning DNA sequencing oligonucleotide design and agarose gel electrophoresis.
• Experience in protein expression purification and characterization including protein expression in bacteria mammalian cells or other cell types and protein characterization techniques such as SDS-PAGE Western blot ELISA SEC SPR and circular dichroism spectroscopy.
• Experience interpreting technical direction from a variety of sources including standardized operating procedures publications and patents.
• Experience in antibody phage display library generation antibody selection and/or antibody characterization would be considered an asset.

Condition of Employment

Reliability Status

For a Reliability Status verification of background information over a period of 5 years is required.

Language Requirements

English

Information on language requirements and self-assessment tests

Assessment Criteria

Candidates will be assessed on the basis of the following criteria:

Technical Competencies

• Strong knowledge in molecular biology and protein biochemistry.
• Ability to prepare manipulate and store biological samples.
• Ability to design and conduct recombinant DNA experiments such as DNA cloning DNA sequencing PCR and nucleic acid purification.
• Ability to design and conduct recombinant protein expression purification manipulation and characterization.
• Knowledge of basic functional assays for antibodies/proteins.

Behavioural Competencies

Competency Profile(s)

For this position the NRC will evaluate candidates using the following competency profile: Technology Support

View all competency profiles

Compensation

From $66126to $91012per annum.

NRC employees enjoy a wide-range of competitive benefits including a robust pension plan comprehensive health and dental coverage disability and life insurance office closure at the end of December and additional supports to enhance your well-being throughout your career and beyond.

Notes

• In 2025 the NRC has been chosen as one of Canadas Top Employers for Young People the National Capital Regions Top Employers and Forbes Canadas Best Employers.
• Relocation assistance will be determined in accordance with the NRCs directives.
• A pre-qualified listmay be established for similar positions for a one year period.
• Preference will be given to Canadian Citizens and Permanent Residents of Canada. Please include citizenship information in your application.
• The incumbent must adhere to safe workplace practices at all times.
• We thank all those who apply however only those selected for further consideration will be contacted.