Scientist II Bioinformatics
Scientist II Bioinformatics
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Asklepios BioPharmaceutical Inc. (AskBio) is a leading clinicalstage gene therapy company founded in 2001 based on the work of adenoassociated virus (AAV) gene therapy visionary and pioneer Jude Samulski PhD. Since that time our commitment to developing lifesaving medicines that can potentially cure genetic diseases has never wavered.
At AskBio weve built a foundation of therapeutic programs AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular central nervous system cardiovascular and metabolic diseases with clinical trials underway for Pompe disease Parkinsons disease and congestive heart failure. Our gene therapy platform includes Pro10 an industryleading proprietary cell line manufacturing process and an extensive AAV capsid and promoter library.
We became a whollyowned independently operated subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park NC. Additionally we have significant operations in Philadelphia PA Columbus OH Scotland France Germany and Spain.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform peoples lives.
Our principles:
Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.
Our values:
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate actively listen openly communicate and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our hold a relentless commitment to advance science and clinical outcomes for our patients families and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest transparent and committed to doing whats right in every situation. Make clear commitments and follow through.
Position Summary
The Scientist II Bioinformatics develops and implements computational methods for analysing proprietary biological data supporting crossfunctional teams with tailored bioinformatics solutions. Will have expertise in omics data analysis statistical methods and scientific programming. The role contributes to innovative computational research in gene therapy advancing AskBios platformenabled product approach. This is a onsite based position in UK Edinburgh reporting to the Sr. Director Bioinformatics and Machine Learning.
Job Responsibilities
- Develop and implement computational methods and algorithms for the analysis of proprietary biological data
- Collaborate with crossfunctional international teams to understand data analysis needs and provide tailored bioinformatics solutions
- Contribute to the design and optimisation of bioinformatics pipelines and workflows to improve data processing and analysis
- Stay up to date with advancements in bioinformatics machine learning and data science integrating relevant approaches into ongoing work
- Communicate findings and recommendations effectively to stakeholders including senior leadership and nonexpert audiences
- Provide mentorship and guidance to junior team members fostering a culture of collaboration and learning
Minimum Requirements
- PhD in bioinformatics computational biology or a related discipline with at least 2 years of postdoctoral or relevant industry experience; or Masters degree in bioinformatics computational biology or a related field with at least 8 years of relevant industry or research experience
- Strong programming skills in Python
- Experience in statistical analysis of DNA sequence and molecular datasets
- Proven ability to communicate complex computational analyses to both technical and nontechnical audience
- Expertise in processing and analyzing omic datasets particularly nextgeneration sequencing (NGS) data
- Familiarity with Unix/Linuxbased systems and commandline environments
Preferred Skills & Abilities
- Experience developing computational methods for biological data analysis
- Experience working with clinical or translational research data
- Proficiency in additional data analysis languages (e.g. R MATLAB)
- Knowledge of containerization tools such as Docker
- Familiarity with integrating multiomics datasets
- Experience with workflow management systems such as Snakemake or Nextflow
- Knowledge of gene therapy and its bioinformatics challenges
- Expertise in structural biology particularly in protein structure modelling interactions and computational structural analysis
- Experience contributing to crossdisciplinary and global research projects
- Familiarity with version control systems (e.g. Git) and collaborative development practices
Asklepios BioPharmaceutical Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race color religion gender sexual orientation gender identity national origin age disability veteran status or any other protected status prohibited under Federal State or local laws. All employment decisions are based on valid jobrelated requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening by calling us ator sending us an email at .
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio through any medium will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio no fee or payment of any kind will be paid to the agency.
Employment Type
Full-Time
