Chief Medical Officer - CMO

Job Description

Job Title: Chief Medical Officer (CMO)
Location: New York or Bostin US
Job Type: Fulltime

About the Company:

We are working with a pioneering biotech company focused on developing transformative therapies for neurological disorders. With a robust pipeline of novel therapies targeting neurodegeneration neurodevelopmental disorders and rare neurological diseases we are committed to delivering breakthrough treatments to patients with high unmet medical needs.

Position Summary:

We are seeking a visionary Chief Medical Officer (CMO) Neurology to lead our clinical and medical strategy. As a key member of the executive leadership team the CMO will be responsible for driving the clinical development of our neurology pipeline overseeing all aspects of medical strategy clinical trial regulatory engagement and external collaborations.

The ideal candidate is an experienced physicianscientist or industry leader with deep expertise in neurology drug development particularly in earlystage clinical programs. This role requires strong strategic thinking scientific acumen leadership capabilities and the ability to navigate the complexities of clinical development in a fastpaced biotech environment.

Key Responsibilities:

Strategic Leadership & Clinical Development Oversight

• Define and execute the overall clinical development strategy for the companys neurology portfolio ensuring alignment with corporate objectives.
• Oversee the design and of earlyphase clinical trials (Phase 1/2 and guide programs through proofofconcept (PoC) and laterstage development.
• Provide expert medical guidance on study design clinical endpoints biomarker strategies and regulatory interactions.
• Lead internal Go/NoGo decisionmaking based on clinical data ensuring rapid and informed development decisions.

Regulatory & External Engagement

• Serve as the primary medical liaison with global regulatory authorities (e.g. FDA EMA) leading IND/CTA submissions regulatory strategy and advisory meetings.
• Develop and maintain strong relationships with Key Opinion Leaders (KOLs) patient advocacy groups and clinical investigators to support trial recruitment and data dissemination.
• Represent the company in scientific regulatory and investor meetings as well as at key medical and industry conferences.

CrossFunctional Leadership & Team Building

• Lead and mentor the Clinical Development and Medical Affairs teams fostering a highperformance innovationdriven culture.
• Collaborate closely with R&D Translational Medicine Commercial Business Development and Regulatory teams to ensure seamless progression from preclinical to clinical development.
• Drive external partnerships with academia CROs and biopharma partners to enhance clinical trial and scientific innovation.

Medical Governance & Risk Management

• Ensure compliance with ethical regulatory and safety standards across all clinical programs.
• Oversee pharmacovigilance activities patient safety monitoring and risk mitigation strategies.
• Provide clinical and medical input for business development including due diligence on potential partnerships or acquisitions.

Qualifications & Experience:

• MD with PhD or with board certification in Neurology or a related field.
• 15 years of experience in clinical development with a strong track record in neurology drug development particularly in earlyphase (FIH Phase 1/2 programs.
• Expertise in neurodegeneration neurodevelopmental disorders or rare neurological diseases is highly preferred.
• Proven experience leading clinical development programs including IND submissions regulatory interactions and clinical trial .
• Strong knowledge of translational medicine biomarkers and precision neurology approaches.
• Demonstrated ability to lead teams in a biotech or pharma environment with experience in small highgrowth organizations.
• Excellent leadership communication and stakeholder engagement skills.

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