Prince Kumar Lat

Prince Kumar Lat

Biostatistician/Data Scientist
Canada

نبذة عني

A passionate and a versatile researcher with extensive experience in bioinformatics and RNA structure coupled with substantial experience in wet lab research, showcasing 8 publications in high impact journals. Cross func…

الخبرة

Biostatistician/Data Scientist

Purpose Life Sciences, Canada
May 2023 - حتى الآن · 3 سنوات 5 أشهر

<p>Leading the development of deep learning transformer model to predict optimal chemical pathway for retrosynthesis of small molecules in drug development<br>
Analysed “TOGETHER” Clinical Trial data with Bayesian statistics, successfully evaluating multiple repurposed drugs for Covid-19, yielding 3 publications<br>
Developed R Shiny web application for interactive data visualization and generation of automated Statistical Analysis Plan (SAP) as per the FDA submission standard<br>
Reviewed and prepared research manuscripts<br>
Collaborated with internal and external teams to ensure successful project completion</p>

Postdoctoral Fellow

BC Cancer, Vancouver, Canada
Jun 2022 - May 2023 · 11 أشهر

<p>Optimized single-cell gDNA NGS library prep and wrote master bash scripts, streamlining procedures such as 'biotinylated gDNA enrichment' in nanolitre volume<br>
Developed antibody based assays for specific ChIP-seq application and performed MD simulations to predict protein/mRNA 3D-fold stability using GROMACS<br>
Developed a bioinformatics pipeline to mitigate the problem of index hopping in directional DNA sequencing library preparation<br>
Designed and executed experiments independently<br>
Focussed on culturing mouse ES cell lines to pioneer a new approach to map DNA replication origins in single-cells</p>

Research Scientist

Flextrapower Tech, Vancouver, Canada
Dec 2021 - May 2022 · 5 أشهر

<p>Engineered an aptamer-based DNA sensor for heavy metal detection in body fluids<br>
Involved in lab management: prepared lab budget/SOP and trained junior scientists</p>

Programmer/IT Consultant

Cognitive Lab, SFU, Canada
Jan 2020 - Apr 2020 · 3 أشهر

<p>Wrote python script, automating large-scale cognitive experiments to efficiently understand human mental behaviour across demographics (race, sex and age)</p>

المهارات

علم الأحياء كيمياء الإحصاء معرفة الكيمياء الحيوية خوارزميات تعلم الآلة لغة البرمجة R برمجة Python التعلم العميق الكيمياء العضوية Python Bash Statistical Analysis Machine Learning SAS MD simulations Protein Modelling RNA-seq WES De-novo assembly Gromacs PyMOL Galaxy rdkit ggplot2 Git Snakemake Docker SQL JIRA NGS High-throughput assays Cell Culture FACS qPCR Problem Solving Documentation Collaboration Multitasking
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