Prince Kumar Lat

Prince Kumar Lat

Biostatistician/Data Scientist
Canada

About Me

A passionate and a versatile researcher with extensive experience in bioinformatics and RNA structure coupled with substantial experience in wet lab research, showcasing 8 publications in high impact journals. Cross func…

Experience

Biostatistician/Data Scientist

Purpose Life Sciences, Canada
May 2023 - Present · 3 years 2 months

Leading the development of deep learning transformer model to predict optimal chemical pathway for retrosynthesis of small molecules in drug development
Analysed “TOGETHER” Clinical Trial data with Bayesian statistics, successfully evaluating multiple repurposed drugs for Covid-19, yielding 3 publications
Developed R Shiny web application for interactive data visualization and generation of automated Statistical Analysis Plan (SAP) as per the FDA submission standard
Reviewed and prepared research manuscripts
Collaborated with internal and external teams to ensure successful project completion

Postdoctoral Fellow

BC Cancer, Vancouver, Canada
Jun 2022 - May 2023 · 11 months

Optimized single-cell gDNA NGS library prep and wrote master bash scripts, streamlining procedures such as 'biotinylated gDNA enrichment' in nanolitre volume
Developed antibody based assays for specific ChIP-seq application and performed MD simulations to predict protein/mRNA 3D-fold stability using GROMACS
Developed a bioinformatics pipeline to mitigate the problem of index hopping in directional DNA sequencing library preparation
Designed and executed experiments independently
Focussed on culturing mouse ES cell lines to pioneer a new approach to map DNA replication origins in single-cells

Research Scientist

Flextrapower Tech, Vancouver, Canada
Dec 2021 - May 2022 · 5 months

Engineered an aptamer-based DNA sensor for heavy metal detection in body fluids
Involved in lab management: prepared lab budget/SOP and trained junior scientists

Programmer/IT Consultant

Cognitive Lab, SFU, Canada
Jan 2020 - Apr 2020 · 3 months

Wrote python script, automating large-scale cognitive experiments to efficiently understand human mental behaviour across demographics (race, sex and age)

Skills

Biology Chemistry Statistics Biochemistry Knowledge Machine Learning Algorithms R Programming Language Script Python Deep Learning Organic Chemistry Python Bash Statistical Analysis Machine Learning SAS MD simulations Protein Modelling RNA-seq WES De-novo assembly Gromacs PyMOL Galaxy rdkit ggplot2 Git Snakemake Docker SQL JIRA NGS High-throughput assays Cell Culture FACS qPCR Problem Solving Documentation Collaboration Multitasking
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