A passionate and a versatile researcher with extensive experience in bioinformatics and RNA structure coupled with substantial experience in wet lab research, showcasing 8 publications in high impact journals. Cross func…
A passionate and a versatile researcher with extensive experience in bioinformatics and RNA structure coupled with substantial experience in wet lab research, showcasing 8 publications in high impact journals. Cross functional collaborator; Proficient in Python and R as denoted by successful completion of 11 real-world machine learning projects with one MD simulation work published in Nature Communications. Strong oral and written communication skills with expertise in writing/editing grant proposals, research manuscripts, and fellowship applications.
<p>Leading the development of deep learning transformer model to predict optimal chemical pathway for retrosynthesis of small molecules in drug development<br>
Analysed “TOGETHER” Clinical Trial data with Bayesian statistics, successfully evaluating multiple repurposed drugs for Covid-19, yielding 3 publications<br>
Developed R Shiny web application for interactive data visualization and generation of automated Statistical Analysis Plan (SAP) as per the FDA submission standard<br>
Reviewed and prepared research manuscripts<br>
Collaborated with internal and external teams to ensure successful project completion</p>
<p>Optimized single-cell gDNA NGS library prep and wrote master bash scripts, streamlining procedures such as 'biotinylated gDNA enrichment' in nanolitre volume<br>
Developed antibody based assays for specific ChIP-seq application and performed MD simulations to predict protein/mRNA 3D-fold stability using GROMACS<br>
Developed a bioinformatics pipeline to mitigate the problem of index hopping in directional DNA sequencing library preparation<br>
Designed and executed experiments independently<br>
Focussed on culturing mouse ES cell lines to pioneer a new approach to map DNA replication origins in single-cells</p>
<p>Engineered an aptamer-based DNA sensor for heavy metal detection in body fluids<br>
Involved in lab management: prepared lab budget/SOP and trained junior scientists</p>
<p>Wrote python script, automating large-scale cognitive experiments to efficiently understand human mental behaviour across demographics (race, sex and age)</p>
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