Principal Scientist, Data Science DDSAI Therapeutics Development Supply

The primary location is flexible to Spring House PA Cambridge; MA; or Madrid or Barcelona Spain.

For candidates interested in Spain please apply to requisition: R-081606

J&J Innovative Medicine develops treatments that improve the health of people worldwide. Research and development areas encompass oncology immunology neuroscience cardiopulmonary and specialty ophthalmology. Our goal is to help people live longer healthier lives. We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market from patients to practitioners and from clinics to hospitals. To learn more about Johnson & Johnson Innovative Medicine visit SUMMARY

The R&D Data Data Science and Artificial Intelligence (DDSAI) organization is seeking a hands-on Principal Scientist Data Science to design build and scale AI/ML simulation forecasting optimization decision intelligence and digital twin capabilities that support decision-making across Drug Product Development & Supply (DPDS) with primary focus on Therapeutics Development & Supply (TDS).

This individual contributor role will partner with development technical operations clinical supply chain finance and digital/data science stakeholders to translate complex scientific operational and planning processes into practical decision intelligence capabilities for TDS. The ideal candidate combines deep expertise in data science operations research scientific computing and software development discipline with a track record of delivering measurable business impact in complex technical environments.

KEY RESPONSIBILITIES

Digital Twin Development & Decision Intelligence

Design build validate and maintain digital twins and decision models of TDS/DPDS operations to support portfolio planning capacity and resource allocation demand/supply planning scenario analysis and operational decision-making.

Apply data science operations research forecasting simulation uncertainty quantification mathematical optimization heuristics and machine learning methods to solve high-value business and scientific planning problems.

Translate complex development manufacturing clinical supply and planning processes into fit-for-purpose computational models that capture uncertainty constraints and cross-functional interdependencies.

Technical Delivery & Software Development Discipline

• Develop robust reusable analytical workflows and modeling assets using Python and modern data science tooling including cloud-based services.
• Apply software engineering best practices including version control modular code design testing documentation reproducibility and code review.
• Use modern development environments including AI-assisted coding tools where appropriate to accelerate delivery while maintaining quality transparency and maintainability.

Cross-Functional Leadership Mentorship & Business Impact

• Partner with scientific technical operations finance and digital stakeholders to define requirements shape analytical solutions and embed outputs into business planning and decision workflows.
• Lead technical work across multiple concurrent projects while remaining a hands-on contributor.
• Communicate model assumptions limitations results and recommendations clearly to technical and non-technical audiences.
• Mentor junior colleagues and provide technical guidance to consultants post-doctoral researchers and external collaborators contributing to project delivery.

QUALIFICATIONS

Required

• Advanced degree in Operations Research Industrial Engineering Applied Mathematics Statistics Computer Science Data Science Chemical Engineering Chemistry Physics or a related quantitative field.
• 3-5 years of relevant experience applying data science operations research simulation forecasting optimization or scientific computing methods to complex R&D manufacturing clinical supply technical operations or business planning problems.
• Strong Python programming skills and demonstrated use of modern analytical development practices including version control testing documentation reproducibility and code review.
• Proven track record of delivering analytical products computational models or decision intelligence tools that influenced business scientific or operational decisions.
• Demonstrated ability to provide technical leadership in cross-functional environments while remaining a hands-on individual contributor.

Preferred

Ph.D. in Operations Research Engineering Applied Mathematics Computer Science Statistics Data Science or a related quantitative discipline.

Experience in pharmaceutical product development CMC technical development manufacturing clinical supply supply chain portfolio planning capacity planning resource planning or regulated life sciences environments.

Experience deploying simulation forecasting optimization or AI/ML-enabled decision tools into business workflows at enterprise scale.

Exposure to developing and/or deploying agent-based AI solutions

Why This Role Is Unique

This is a rare opportunity to grow in one of the worlds most ambitious and fast-growing R&D Data Science organizations shaping how advanced modeling simulation and optimization transform decision-making across Drug Product Development & Supply with direct impact on Therapeutics Development & Supply. Your work will directly improve how Johnson & Johnson plans and executes its development portfolio allocates critical resources and accelerates delivery of next-generation therapies to patients globally.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

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