AI Security Operations Engineer

AstraZeneca


Job Location:

Gaithersburg, MD - USA

Monthly Salary: $ 136044 - 204066
Posted on: 13 days ago
Vacancies: 1 Vacancy

Job Summary

TheAI Security Operations Engineeris responsible forsecuring operationalizing and scalingAI Generative AI and Agentic AI systemsacross the enterprise. This role bridgessecurity architecture AI governance and operational security ensuring AI systems are designed deployed andmonitoredwithsecuritybydesignand runtime assurance.

This roleoperatesas ahandsontechnical leaderand trusted advisor to engineering AI and business stakeholders translating AI risk into actionable security controls without slowing innovation.

Key Responsibilities

  • Leadsecurity design and operational oversightfor AI Generative AI and Agentic AI initiatives across the enterprise

  • Define and operationalizeAI security frameworks standards and review processesthat govern model lifecycle data usage and autonomous behavior

  • ConductAIfocusedsecurity architecture reviewsand threat modeling toidentifyand mitigate risks before deployment

  • Support andmonitoragentic and autonomous AI workflows ensuring guardrails accountability and runtime visibility

  • Partner with AI leadership and accelerator programs to enablesecure AI adoption at scale

  • Translate complex AI and cybersecurity risks intoclear business andpatientimpactnarrativesfor senior leadership

  • Contribute to and evolveenterprise AI governance programs aligning with global regulatory expectations (e.g.NIST AI RMFEU AI Act privacy frameworks)

  • Enable continuous improvement of AI security operations throughautomation metrics and repeatable processes

Required Qualifications

  • Bachelors Degree

  • 7 years of experience incybersecurity architecture security engineering or security operations

  • Demonstratedexpertisesecuringcloud hybrid andonpremenvironments(AWS Azure GCP)

  • Handsonexperience withAI/ML security Generative AI and Agentic AI concepts

  • Proven ability to build and scaleenterprise security frameworksfor emerging technologies

  • Strong background inthreat modeling risk analysis and secure solution design

  • Experience advising and influencingmultiple stakeholders across hundreds of initiativesannually

  • Ability tooperateindependently while shaping strategy and execution

Preferred / Differentiating Skills

  • Experience designing or contributing toenterprise AI cybersecurity frameworks

  • Background supportingAI governance and accelerator programs

  • Knowledge ofglobal regulatory and compliance requirements(NISTAI RMFEU AI Act GDPR HIPAA PCIDSS)

  • Experience inlife sciences healthcare or highly regulated environments

  • Certifications inAI governance or cybersecurity(e.g.AIGPCISSPCISM CISA)

What Success Looks Like

  • AI initiatives move faster because security isembedded early not reviewed late

  • Agentic AI systems are deployed withclear guardrails monitoring and accountability

  • Security reviews scale acrosshundreds of AI andnonAIprojects annuallywithout becoming a bottleneck

  • Leadership has clear visibility intoAI risk posture and readiness

When we put unexpected teams in the same room we unleash bold thinking with the power to encourage life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

The annual base pay for this position ranges from $136044.00 - $204066.00 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Are you ready to bring new insights and fresh thinking to the tableFantastic! We have one seat available and we hope its yours. Apply today.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.

Date Posted

05-Jun-2026

Closing Date

19-Jun-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.


Required Experience:

IC

TheAI Security Operations Engineeris responsible forsecuring operationalizing and scalingAI Generative AI and Agentic AI systemsacross the enterprise. This role bridgessecurity architecture AI governance and operational security ensuring AI systems are designed deployed andmonitoredwithsecuritybydes...

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AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more

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