Principal Statistical Methodologist

Make your mark for patients

We are looking for a Principal Statistical Methodologist who is curious collaborative and strategic to join our Statistical Innovation team within Biometric and Data Sciences (BDS) based in Slough (UK).

About the role
You will help shape how evidence is generated and communicated across the drug development lifecyclefrom early clinical development to regulatory approval and lifecycle work. You will provide expert statistical consultation on trial design and analysis develop and apply advanced methods and translate complex quantitative concepts into clear insights for cross-functional partners. You will also contribute to scientific communications and external collaboration through publications and industry initiatives.

Who you will work with
You will be part of a team that provides statistical consultancy across therapy areas and development stages partnering closely with colleagues in clinical development regulatory strategy data science and medical affairs. The team values curiosity and problem solving practical innovation clear communication and collaborationbringing novel statistical approaches into real study decisions and sharing learnings with the wider scientific community.

What you will do

• Provide statistical consultation on clinical trial design and analysis across multiple development stages and therapy areas.
• Develop and implement innovative statistical approaches including model-based methods using frequentist and Bayesian techniques.
• Run or guide advanced analyses and simulations to inform design options sample size and power trade-offs.
• Communicate complex quantitative topics clearly using visuals simulations and plain language for diverse audiences.
• Contribute to internal learning by delivering training on advanced statistical concepts for non-statisticians and statisticians.
• Contribute to the groups external profile through scientific publications conference presentations and participation in cross-industry initiatives and working groups.

Interested Here is what we are looking for

• Doctoral degree in statistics mathematics or a closely related scientific discipline.
• 3 years of experience working in biostatistics within the pharmaceutical industry. Experience in statistical methodology for clinical development (early to late stage) is an advantage.
• Expertise in advanced statistical methods and innovative trial design; experience with causal inference and estimands is an advantage.
• Strong statistical programming skills (R preferred; equivalent tools considered).
• Sound knowledge of ICH guidelines and understanding of regulatory requirements from major health authorities.
• Ability to work effectively with autonomy manage multiple priorities and deliver timely high-quality outputs.

Are you ready to go beyond to create value and make your mark for patients If this sounds like you then we would love to hear from you!

About us
UCB is a global biopharmaceutical company focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe inspired by patients and driven by science.

Why work with us
At UCB we dont just complete tasks we create value. We arent afraid to push forward collaborate and innovate to make our mark for patients. We have a caring supportive culture where everyone feels included respected and has equal opportunities to do their best work. We go beyond to create value for our patients and always with a human focus whether thats on our patients our employees or our planet. Working for us you will discover a place where you can grow and have the freedom to carve your own career path to achieve your full potential.

At UCB weve embraced a hybrid-first approach to work bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.