Lead Bioinformatics Engineer (Hyrbid)

Pay Range: $155000.00 - $175000.00 / year

Salary offers are based on a wide range of factors including relevant skills training experience education and where applicable certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.

Benefits Information:

We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy happy lives. Our pay and benefit plans have been designed to promote employee health in all respects physical financial and developmental. Depending on whether it is a part-time or full-time position some of the benefits offered may include:

Day 1 Medical supplemental health dental & vision for FT employees who work 30 hours

Best-in-class well-being programs

Annual no-cost health assessment program Blueprint for Wellness

healthyMINDS mental health program

Vacation and Health/Flex Time

6 Holidays plus 1 MyDay off

FinFit financial coaching and services

401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service

Employee stock purchase plan

Life and disability insurance plus buy-up option

Flexible Spending Accounts

Annual incentive plans

Matching gifts program

Education assistance through MyQuest for Education

Career advancement opportunities

and so much more!

At Quest we are on a continuous journey of discovery and development. Its this attitude that has made us an industry leader and the #1 Diagnostic Lab in the US. For those joining us we offer exciting and fast-moving career opportunities where you can affect change at a rate unheard of in many organizations of our size and scope. While we invest in and develop technology to drive our innovations our ongoing success relies on our people.

Quest Diagnostics Specialty Genetics products provide specific answers that clinicians need to deliver the appropriate diagnostic and prognostic care to their patients. You will work for the world leader in the industry with a career where you will have the opportunity to collaborate and affect change while expanding your leadership skills and technical knowledge. You can make a real impact in a market that is growing and developing.

This position is in our Bioinformatics Solutions Engineering group part of the Research and Development organization in Molecular Genomics & Oncology unit. The team supports genetic/genomic testing in a highly regulated CAP/CLIA laboratory environment primarily using short and long-read sequencing as the basis of evidence. The right candidate will know how to balance innovation standards and quality with a practical understanding of when each is appropriate. The Bioinformatics Solutions Engineering group is a cross-functional unit focusing on end-to-end design develop document validation and launching of new high quality diagnostic tests and services for the benefit our patients.

This professional will work in a Hybrid capacity requiring 3 days onsite at our Marlborough MA facility.

• Lead technical design implementation and delivery of projects aiming to launch new diagnostic tests and services. Act as technical owner for your project being responsible for the end-to-end solution from technical side.

• Work with cross-functional partners from business operations IT R&D lab geneticists medical directors and other bioinformatics stakeholders to create solutions that meet business and operational requirements.

• Lead solution architecture and interface design including system architecture for bioinformatics and detailed data flow mapping.

• Collaborate with stakeholders to ensure compliance of the solution with internal and external IT security and clinical policies and processes.

• Work with bioinformatics domain leaders to select appropriate technology platforms for each step in the diagnostic process.

• Oversee end-to-end testing and diagnostic test validation activities with the project team.

• Lead the technical documentation and plan and execute handover to operations to ensure effective launch and operation of the solution.

• Work with project management and report on progress analyze risks and escalate issues to ensure accurate project management.

• BS with 7 years of experience MS with 4 years of experience or PhD with 3 years of experience in an industrial or academic setting working with clinical and biological data or equivalent and underlying technologies including bioinformatic methods database development query/scripting/programming languages cloud development agile methodology DevOps and other data analysis tools.

• At least 5 years of experience working in a regulated industrial life sciences environment.

• At least 4 years of professional software development or technical engineering experience

Preferred Work experience and Skills:

• Thorough understanding of end-to-end diagnostic process including ordering wet lab dry lab result interpretation and result and data delivery.

• Experience with solution design system architecture solution architecture data flow modeling.

• Experience in leading technical design and implementation of complex projects.

• Experience with sequencing data analysis bioinformatics variant data analysis.

• Knowledge of bioinformatics tools and workflow managers for sequencing data analysis and quality control.

• Experience working with SQL and NoSQL databases.

• Experience with designing and working with application programming interfaces (e.g. JSON based RESTful APIs).

• Experience with designing and implementing solutions in the cloud. AWS experience is preferred.

• Experience of working in clinical diagnostics setting (regulations controlled processes diagnostic test validation environment management).

• Solid understanding of human genetics and oncology in diagnostic setting.

• Solid understanding of web lab process for DNA sequencing and working with or developing LIMS systems.

• Infrastructure management: Terraform AWS CDK.

• Architecture design: Microsoft Visio DrawIO similar for crafting architecture diagrams.

• Programming Languages: Python javascript/typescript R etc.

• Containerizing: Docker

• Web Frameworks: Python Flask React Native Bootstrap

• Reporting: R Markdown Jupyter Notebook

• Visualization: Experience with any of ggplot2/tidyverse Plotly matplot lib Tableau

• Source Control: Git

• CI/CD: Gitlab CI/CD Github CI/CD

Education

• Bachelors Degree Required

• Masters Degree or PhD Preferred