Senior Scientist – Cell Therapy Safety
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Job Location:
Monthly Salary:
Posted on:
20 hours ago
Vacancies:
1 Vacancy
Job Summary
Do you have a background in cell therapy safety assessment and want to shape the safety strategy for innovative cellular therapeutics Are you excited to expand yourexpertisein the non-clinical safety assessment of next-generation cellular modalities If yes AstraZeneca could have the role for you.
About the role
We areseekinga highly motivated Senior Scientist to join our laboratory-based Cell TherapySafety Teamwithin Clinical Pharmacology & Safety Sciences (CPSS). This role is based at ourstate-of-the-artDiscovery Centre in Cambridge UK offering a collaborative environment across disciplines to drive innovation in 21st-century pharmaceutical research.
At AstraZeneca we value diverse perspectives and inclusive collaboration. We believe teams are most creative when individuals contribute different ideas and experiences in an environment where those differences are welcomed and respected. This is how we foster continuous innovation learning and growthfor our people and for patients.
Whatyoulldo
You will primarily support our growingcellular medicineportfolio;includingautologousallogeneicand in vivo CAR-T. You will design and execute assays and applyimmunology/cell biologyapproaches to develop methods for assessingpre-clinicalsafety.
Key responsibilities include:
Model development: Develop andvalidatenew in vitro models to predict and assess toxicity immunogenicity and tumorigenicity for cellular therapeutics; contribute to broader non-clinical toxicology packages for novel modalities.
Scientific problem-solving:Identifyand solve complex scientific problems;championscientific and technological innovations that advance strategic capabilities.
External engagement: Collaborate with leading academics; publish in high-quality journals; actively contribute to scientific networks and communities.
Innovation: Drive innovation to support internal and external presentations and publications to strengthen AstraZenecas scientific leadership.
Cross-functional collaboration: Work closely with scientists across CPSS and partnered functions to translate biological insights into safety strategies for pioneering therapeutics.
Essential qualifications and experience
PhD or equivalent in immunology cellular biology or a related discipline.
Strong scientifictrack recordinimmunology andcell therapydevelopment with practical experience inflow cytometry cell therapy discovery andideallytoxicology assessment; post-doctoral experience preferred.
Experience designing and/or executing in vitro and/or in vivo studies todeterminesafety and/or efficacy of cellular therapeutics.
Preferably experience as a safety scientist incell therapy development from project conception throughtocandidateselection.
Demonstrated ability to work effectively in multi-disciplinary teams withstrong communicationskills (presenting manuscript preparation influencing relationship building).
Excellent publication recordcommensuratewith career stage.
Ability tooperatein compliance with Good Laboratory Science standards Safety Health & Environment requirements and relevant external regulations.
Who you are
You are a motivated creative and innovative scientist with a collaborative team-oriented mindset. You enjoy solving complex problems with a goal-focused approach and havestrong communication
and presentation skills. You thrive in an open positive and collaborative working environment.
Why AstraZeneca
At AstraZeneca curiosity and courage drive our science.Wereinspired by the possibility of doing what has not been done before. Empowered to step up we challenge fear of failure explore the biology of complex diseases and make bold decisionscelebrating successes and learning from setbacks along the way.We have the ambition to be a world leader in cell therapydevelopment to meet the unmetcurativeneeds in oncology and autoimmune diseases.
Whatsnext
Step into a role where your science sets the safety bar for pioneering cell therapiesbring your curiosity and rigor and make your impact now!
To find out more:
Group site: social media Follow us on LinkedIn: AstraZeneca
Inclusion & Diversity: site: Posted
24-fev.-2026Closing Date
09-mar.-2026Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
