AskBio Inc. a wholly owned and independently operated subsidiary of Bayer AG is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular central nervous system cardiovascular and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure limb-girdle muscular dystrophy multiple system atrophy Parkinsons disease and Pompe disease. AskBios gene therapy platform includes Pro10 an industry-leading proprietary cell line manufacturing process and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park North Carolina and European headquarters in Edinburgh Scotland the company has generated hundreds of proprietary capsids and promoters several of which have entered pre-clinical and clinical testing.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform peoples lives.
Our principles:
Advance innovative science by pushing boundaries.
Bring transformative therapeutics to patients in need.
Provide an environment for employees to reach their fullest potential.
Our values:
Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
Cultivate Collaboration. Strive to be the best teammate actively listen openly communicate and embrace diverse points of view.
Embrace Responsibility. We are humbled by the enormity of our hold a relentless commitment to advance science and clinical outcomes for our patients families and caregivers.
Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
Act with Uncompromising Integrity. Be honest transparent and committed to doing whats right in every situation. Make clear commitments and follow through.
Position Summary
This internship provides an opportunity for a highly motivated student to gain hands-on experience applying machine learning to real biological data within a gene therapy research environment. The intern will work within the Bioinformatics and AI/Machine Learning team to integrate a next-generation machine learning model for enhancer prediction into AskBio proprietary bioinformatics platform PromPT.
The role will focus on building an end-to-end user-facing ML pipeline including data ingestion model integration visualisation of results and downstream biological analysis in close collaboration with bioinformaticians and experimental scientists. The intern will be supported through structured mentoring and regular feedback and will deliver a final presentation and live demonstration of the integrated pipeline and its applications.
The intern will report to the Senior Director Bioinformatics and AI/Machine Learning and will be based in the Edinburgh office.
Job Responsibilities
Support the integration of a next-generation machine learning model for enhancer prediction into an existing bioinformatics platform
Learn how machine learning models are applied to biological sequence data in a gene therapy context
Review and understand existing bioinformatics pipelines within the PromPT platform
Partner with bioinformaticians ML and experimental scientists to gather user requirements and feedback
Assist in developing a simple user interface for model input and configuration
Develop output visualisations and summary analyses to support biological interpretation of model results
Participate in code reviews documentation and best-practice software development workflows
Assist in testing validation and performance assessment of the integrated pipeline
Communicate progress clearly through regular updates and discussions with the project team
Collect and analyse feedback from users to refine pipeline functionality and usability
Present a final demonstration of the integrated ML pipeline and its applications at the end of the internship
Minimum Requirements
Must be pursuing a Doctorate degree in Informatics Bioinformatics Data or Computer Science AI or Machine Learning or a related field
Must have completed their first year at the time of application
Coursework or academic experience in one or more of the following: bioinformatics machine learning data science or computational biology
Basic programming experience in Python or a similar scientific programming language
Familiarity with fundamental concepts in machine learning or statistical data analysis
Interest in applying computational methods to biological or genomic data
Strong analytical and problem-solving skills
Ability to communicate technical ideas clearly to both technical and non-technical audiences
Organised curious and eager to learn in a collaborative research environment
Available to work full-time on-site in the Edinburgh office during the summer internship period
Preferred Education Experience and Skills
Prior research internship or project experience in bioinformatics machine learning or data science
Exposure to biological sequence data (e.g. DNA RNA or genomic datasets)
Familiarity with Linux or command-line environments
Experience with data visualisation libraries or tools
Awareness of software development best practices such as version control (e.g. Git)
Interest in gene therapy genomics or computational biology research
AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race color religion gender sexual orientation gender identity national origin age disability veteran status or any other protected status prohibited under Federal State or local laws. All employment decisions are based on valid jobrelated requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening by calling us at or sending us an email at .
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio through any medium will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio no fee or payment of any kind will be paid to the agency.
Required Experience:
Intern