Principal Lead, Technical Program Manager (Drug Design and Medical Research)

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights faster breakthroughs and life-changing medicines with an ambition to solve all disease.

The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.

Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals while being a part of an inspiring and collaborative culture.

The world we want tomorrow is the one were building today. It starts with the culture at this company. It starts with you.

About Iso

Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed.

Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AIs powerful capabilities we can use it to model complex biological phenomena to help design novel molecules anticipate how drugs will perform and develop innovative medicines to treat and cure some of the worlds most devastating diseases.

We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design.

Every day and with each new breakthrough were getting closer to the promise of digital biology and achieving our ambitious mission to one day solve all disease with the help of AI.

Your impact

As our Drug Design and Medical Research (DDMR) function continues to grow and scale we are excited to have the opportunity to hire an experienced Principal Technical Program Manager to partner closely with our Chief Scientific Officer (CSO) and Chief Research Officer (CRO) and lead some of our most critical Drug Design initiatives here at Iso.

As a senior member of the Technical Program Management (TPM) team you will be accountable for driving progress across the key strategic areas of our (DDMR) function. You will provide strategic leadership and hands-on management partnering with DDMR leadership to integrate across our key strategic DDMR areas in alignment with company-level goals elevating and evolving our DDMR operating model as we progress towards our mission. You will partner with key internal cross-functional stakeholders including our Principal TPM Lead for AI & Tech Alliance Management Finance Legal and Business Development to deliver on our ambitious mission.

This is a pivotal role where you will not only lead complex high-impact programs but also shape the future of our DDMR technical program management discipline. If you are a proven leader looking to make a significant impact on the trajectory of an organisation this is an unparalleled opportunity.

What you will do

• Lead Technical Program Management across our complex company-wide AI-first Drug Design initiatives overseeing the entire lifecycle from strategic planning and resourcing through to execution risk management and successful delivery. Youll bring an interdisciplinary approach to this ensuring integration and connection with AI Tech Finance Legal and other internal stakeholders.
• Partner with the Chief Scientific Officer (CSO) and Chief Research Officer (CRO) to design communicate and implement a functional operating model that seamlessly integrates across our DDMR strategic areas and aligns execution with overarching company goals in particular innovating around capacity and resource management as we scale our portfolio.
• Proactively identify risks gaps pain points and opportunities prioritise them and get the buy-in to effect change and elevate how DDMR operates keeping things lean and minimising work for others.
• Partner with and sometimes act as the voice of the CSO and CRO on the strategic development of our Drug Design portfolio planning for the future in alignment with company direction ambitions and strategy including collaborating on exploratory strategic questions and initiatives.
• Leverage data to strategise identify areas for process and program improvement and plan for future significant programs.
• An excellent communicator youll independently gather input and develop and translate content for the CSO and CRO for forums including Isos Executive Leadership Team and the Board.
• Act as a subject matter expert thought partner and technical leader within the TPM discipline including working with the Principal Lead TPM for AI & Tech to identify define and implement program management standards and best practices across the wider organisation.
• Align and partner with the Alliance Management team to ensure effective collaboration between both departments and ensure consistency in how both partnered and internal programs are managed.
• People management of individuals in the DDMR TPM discipline fostering a culture of high performance and enabling them to deliver in their strategic areas. Youll role model a growth mindset by pursuing the latest industry thinking and using new concepts to enhance functional practices.

Skills and qualifications

Essential:

• Academic background in Biology Chemistry or a related discipline; Extensive industry experience successfully leading complex multi-disciplinary drug design programs from inception to key milestones.
• Deep expertise in the drug discovery and development process with a proven ability to translate scientific and technical goals into actionable strategic plans.
• Proven track record of designing implementing and refining program management frameworks and best practices within a growing organisation.
• Expertise in strategic risk management including the ability to identify mitigate and clearly communicate program risks to executive leadership.
• Demonstrated ability to lead and influence cross-functional teams in a fast-paced ambiguous and constantly changing environment.
• Exceptional communication and stakeholder management skills with proven ability to engage and influence at all levels including executive leadership.
• Significant experience managing budgets including planning forecasting troubleshooting and identifying efficiencies.
• A strategic and data-driven mindset with experience using data to inform and influence strategy drive improvements and deliver on company-level annual goals.

Nice to have:

• Scientific MSc or PhD strongly preferred.
• Formal program management qualification (e.g. PMP PRINCE2)
• Proficiency with program management and collaboration software such as Jira and Confluence.

Culture and values

We are guided by our shared values. Its not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.

Thoughtful
Thoughtful at Iso is about curiosity creativity and care. It is about good people doing good rigorous and future-making science every single day.

Brave
Brave at Iso is about fearlessness but its also about initiative and integrity. The scale of the challenge demands nothing less.

Determined
Determined at Iso is the way we pursue our goal. Its a confidence in our hypothesis as well as the urgency and agility needed to deliver on it. Because disease wont wait so neither should we.

Together
Together at Iso is about connection collaboration across fields and catalytic relationships. Its knowing that transformation is a group project and remembering that what were doing will have a real impact on real people everywhere.

Creating an extraordinary company

We believe that to be successful we need a team with a range of skills and talents. Were building an environment where collaboration is fundamental learning is shared and every employee feels supported and able to thrive. We value unique experiences knowledge backgrounds and perspectives and harness these qualities to create extraordinary impact.

We are committed to equal employment opportunities regardless of sex race religion or belief ethnic or national origin disability age citizenship marital domestic or civil partnership status sexual orientation gender identity pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation please do not hesitate to let us know.

Hybrid working

Its hugely important for us to share knowledge and build strong relationships with each other and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model and would require you to be able to come into the office 3 days a week (currently Tuesday Wednesday and one other day depending on which team youre in). If you have additional needs that would prevent you from following this hybrid approach wed be happy to talk through these if youre selected for an initial screening call.

Please note that when you submit an application your data will be processed in line with our .

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