Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) a serious liver disease that can progress to cirrhosis liver failure need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.
Madrigals medication Rezdiffra (resmetirom) is a once-daily oral liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).
Our success is driven by our people. We are building a dynamic inclusive and high-performing culture that values scientific excellence operational rigor and collaboration. To support our continued growth we are strengthening our workforce strategy to ensure we have the right talent at the right time in the right way.
Director Commercial Real Estate & Workplace Safety
Location: Conshohocken PA
Contract Position
Position Summary
The Director Commercial Real Estate & Workplace Safety will oversee the planning design and execution of Madrigals new 65000-square-foot corporate office buildout in Conshohocken PA and 53000 square-foot office in Waltham PA ensuring the project is delivered on time within budget and aligned with company standards. This leader will also develop and implement comprehensive Environmental Health & Safety (EHS) OSHA compliance and ergonomics programs to support a safe sustainable and productive workplace environment that align with real estate facilities and employee experience objectives.
This is a hands-on leadership role requiring strong project management vendor oversight construction administration and strategic facilities planning experience within a corporate setting (no labs or manufacturing)
Key Responsibilities
Real Estate & Construction Project Management
Lead the day to day coordination of the corporate offices projects from design and permitting through construction occupancy and post-move stabilization ensuring alignment with overall real estate strategy and design standards established by Executive Director
Manage cross functional project activities across architecture design engineering and construction partners to keep deliverables on track and within scope.
Oversee project logistics including budget tracking documentation RFP coordination change order processing maintaining transparency and accountability.
Partner with IT HR and Finance to ensure technology workspace design and budget alignment.
Monitor project schedules and milestones ensuring timely delivery and proactive issue resolution.
Coordinate move management furniture procurement signage and occupancy planning.
Environmental Health Safety & Ergonomics
Develop and implement a comprehensive EHS program for corporate office operations (no lab/manufacturing scope).
Ensure compliance with OSHA local building codes and other applicable regulations.
Lead ergonomics assessments and programs to enhance employee health safety and comfort.
Partner with HR and Facilities to drive workplace safety training and emergency preparedness initiatives.
Establish metrics audits and continuous improvement programs for safety performance.
Oversee sustainability and environmental initiatives aligned with corporate responsibility goals both domestically and internationally
Strategic Facilities Planning & Operations
Coordinate global real estate operations including lease documentation renewals data management ensuring portfolio accuracy and compliance. Contribute to the evolution of Madrigals workplace strategy that supports growth employee experience and hybrid work models.
Support long-term space planning and real estate portfolio management frameworks.
Manage relationships with property owners landlords and key vendors.
Lead workplace policy development around space usage health & safety and facilities operations ensuring quality and accountability
Track KPIs for operational efficiency cost control and employee satisfaction.
Support initiatives that enhance the employee workplace journey through technology design and services (e.g. visitor management systems space planning and service request platforms).
Qualifications
Bachelors degree in Construction Management Engineering Architecture Facilities Management or related field; advanced degree preferred.
14 years of progressive experience in commercial real estate project management and corporate facilities leadership.
Proven success delivering large-scale corporate office buildouts (50000 sq. ft.) on time and within budget.
Strong knowledge of EHS OSHA compliance and ergonomics programs.
Excellent vendor management negotiation and contract administration skills.
Demonstrated ability to collaborate across executive HR finance and IT functions.
Experience in the biopharma or life sciences corporate sector (non-lab) strongly preferred.
Exceptional communication problem-solving and leadership skills.
PMP or related project management certification preferred.
Strong background in space planning workplace technology and office services programs.
Ability to work onsite 5 days a week in Conshohocken PA.
All full-time employees receive equity which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.
Full-time employees are also eligible for comprehensive benefits including flexible paid time off medical dental vision and life/disability insurance and 401(k) offerings (i.e. traditional Roth and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance legal services and other addition we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal state and local laws.
We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact
Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications merit and business need. Applicants will receive consideration for employment without regard to race ethnicity color religion sex gender identity sexual orientation national origin age disability protected veteran or disabled status or other characteristic protected by applicable federal state or local law.
Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.
Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.
Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals Hiring Managers seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigals name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g. fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.
Please also note that any correspondence with regard to employment would come from an authorized email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses with Madrigal misspelled have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to .
Required Experience:
Director