Manager, Single Cell Research & Operations

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profile Job Location:

Cambridge, MA - USA

profile Monthly Salary: Not Disclosed
Posted on: 2 days ago
Vacancies: 1 Vacancy

Job Summary

General information

Location
Cambridge MA
Ref #
43493
Job Family
Research
Workplace
On-Site
Date published
01/07/2026
Time Type
Full time
Pay Range
104000 - 145333 Usd Annual

Description & Requirements

The Manager Single Cell & Research Operations will be responsible for implementing changes into both clinical and research processes providing scientific leadership for new experimental design interpreting data and ensuring the development of robust operational processes that align with scientific and organizational goals.

Characteristic Duties:

Process Implementation & Workflow Management

Responsible for implementing changes to New Protocols & Products and Workflow Changes.

Plan validation experiments assess changes statistically and work with Automation LIMS and SQM to implement process changes.

Document work performed and maintain quality standards including training lab teams in a timely manner.

Troubleshooting across the entire area of focus.

Assist with supply chain alternatives create reagent phase-in QCs and be responsible for ordering new reagents.

Maintains up-to-date Bills of Materials related to any process changes or updates and monitors usage.

Scientific Design & Research Contribution

Designs new experiments with more complex and moderately advanced scientific knowledge.

Interprets data presents results of research and draws conclusions regarding presented material and nature of work.

Understands how to build processes that are robust while mindful of how they may impact future processes and fit into scientific and organizational goals.

Makes significant contributions to scientific papers reports posters and presentations.

Participates in the writing of grant proposals and patent applications.

Participates in external activities such as scientific conferences technical meetings invited symposia etc.

Communication & Collaboration

Works in collaboration with the Director Process Development to approve changes and ensure they meet long-term goals.

Collaborate with various teams (Quality & Compliance Automation LIMS SQM GS Lab team ODI) to assess timelines workflows and communicate project updates needs and issues.

Works closely with the Supervisor/General Supervisor daily to communicate project updates resource needs issues etc.

Education Mentoring & Supervision

May train supervise or mentor junior members of the team.

Work with GS to identify competent PDAs to work with on experiments and delegate tasks to.

Listen to feedback from the lab and assess feasibility of requested changes.


Qualification Requirements:

PhD required

At least 5 years of related experience working in a research lab focusing on lab histology genomics molecular biology flow cytometry and imaging.

At least 3 years of management related experience overseeing the work of others in a lab setting.

Experience with all commercial single cell RNA assays including but not limited to 10X Genomics BD Rhapsody and Fluent

Experience with library construction and sequencing is required
Strong understanding of histology best practices and instrumentation

Demonstrated ability to design and optimize flow cytometry panels including high parameter spectral panels

Knowledge of spatial techniques and current instrumentation


The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to relevant skills experience education qualifications and other factors permissible by law.
At Broad your base pay is just one part of a comprehensive total rewards package. From day one this role offers a competitive benefits package including medical dental vision life and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race national origin religion age color sex disability protected veteran status or any other characteristic protected by local state or federal laws rules or regulations.

Should you need a reasonable accommodation to complete the application or interview process please contact for assistance.


Required Experience:

Manager

General information Location Cambridge MA ...
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Key Skills

  • Quantitative Research
  • Spss
  • Clinical Research
  • Data Collection
  • Clinical Trials
  • Research Experience
  • Statistical Software
  • Survey Design
  • Qualitative Research
  • Market Research
  • Research & Development
  • Project Coordination

About Company

Broad Institute is a multidisciplinary community of researchers on a mission to improve human health.

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