Chemist (often at Bristol Myers Squibb) develops optimizes and scales up chemical processes for drug manufacturing involving synthetic/analytical chemistry process development data analysis and troubleshooting complex reactions for new therapies (small molecules peptides etc.) requiring strong organic chemistry skills analytical techniques (NMR MS Chromatography) and collaboration with engineering/manufacturing teams to ensure safe economical and quality production from lab to clinical scale.
Key Responsibilities (Examples from BMS):
Process Development: Design and improve synthetic routes for drug candidates.
Scale-Up: Develop knowledge for transitioning processes from lab to clinical manufacturing.
Analysis & Characterization: Use techniques like chromatography NMR Mass Spec (MS) IR spectroscopy to purify and identify compounds.
Data Management: Analyze compile and share experimental data with project teams.
Collaboration: Work closely with analytical chemists and engineers.
Problem Solving: Troubleshoot complex chemical and manufacturing issues.
Documentation: Support regulatory filings with process knowledge.
Typical Qualifications:
Education: PhD or MSc in Organic Chemistry or related field.
Experience: Strong background in synthetic organic chemistry reaction mechanisms purification and characterization.
Skills: Excellent problem-solving data analysis technical writing and communication skills.
Specific Experience (May vary): Radiochemistry gloveboxes ICP-MS electrochemistry etc. for specialized roles.
In essence a BMS Chemist bridges the gap between early-stage drug discovery and large-scale medicine production ensuring efficient safe and high-quality chemical processes.