Director, Data Architecture Development

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) a serious liver disease that can progress to cirrhosis liver failure need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigals medication Rezdiffra (resmetirom) is a once-daily oral liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic inclusive and high-performing culture that values scientific excellence operational rigor and collaboration. To support our continued growth we are strengthening our workforce strategy to ensure we have the right talent at the right time in the right way.

Title: Director Commercial Data Architecture Development
Department: Commercial Data & Analytics
Location: Conshohocken PA or Waltham MA (Hybrid)
Reports To: Senior Director Commercial Data & Analytics
Employment Type: Full-time

Job Purpose

The Director Commercial Data Architecture Development will lead key development initiatives within the scope of Madrigals Commercial Data Warehouse (CDW). This hands-on technical leader will serve as both architect and team lead for developers driving the design and implementation of scalable high performance data solutions that enable commercial reporting analytics and data-driven decision-making.

This position plays a critical role in defining the foundation of Madrigals commercial data ecosystem and ensuring alignment with business needs data governance standards and technical best practices. The role reports to the Senior Director Commercial Data & Analytics.

Essential Functions

• Lead the design build and implementation of key programs leveraging Microsoft Fabric Databricks Synapse and related tools.
• Serve as architect and technical team lead providing hands-on development and guidance to data engineers in building efficient scalable data pipelines.
• Define and implement data architecture frameworks aligned with Medallion (Bronze Silver Gold) principles.
• Design and oversee ETL/ELT processes for transformation of commercial datasets.
• Maintain data quality integrity and governance processes across all commercial data assets.
• Collaborate with Commercial Operations Market Access Analytics and IT teams to ensure the data environment supports reporting and analytical needs.
• Define data modeling standards master data management approaches and harmonization across multiple data domains.
• Develop and maintain metadata management and documentation for the Commercial Data Warehouse.
• Partner with internal and external technology resources to optimize performance and scalability.
• Continuously evaluate and enhance architecture design to meet evolving business and analytical requirements.

Qualifications

Required:

• Bachelors degree in Computer Science Information Systems Data Engineering or a related discipline.
• Minimum of 15 years of experience in pharmaceutical commercial data management data engineering or data architecture roles.
• Proven track record designing and developing commercial data warehouses in cloud environments preferably Microsoft Azure.
• Expertise with Azure Synapse Databricks Fabric SQL and Power BI integration.
• Deep understanding of pharmaceutical commercial datasets including:
  • Patient-level data (APLD): IQVIA Komodo PurpleLab etc.
  • Formulary data: MMIT
  • Projected national data: Xponent NSP NPA etc.
  • International data: MIDAS
  • Drug distribution data: IQVIA DDD
  • Reference data: OneKey OpenData
  • Specialty pharmacy / Specialty distributor data (SP/SD)
• Strong understanding of data modeling performance tuning and Medallion architecture design principles.
• Hands-on technical development experience with the ability to function as both architect and lead developer.
• Excellent problem-solving communication and cross-functional collaboration skills.

Preferred:

• Experience within or providing consulting support for launch-stage or growth-stage biotech organizations.
• Familiarity with data tokenization and privacy compliance (e.g. Datavant).
• Experience implementing data governance frameworks and metadata management.
• Demonstrated ability to mentor and provide technical direction to development teams.

Madrigals Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

All employees receive equity which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidates qualifications skills education experience business needs and market demands. The base salary range for this position is $212000 - $259000 per year

All full-time employees receive equity which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits including flexible paid time off medical dental vision and life/disability insurance and 401(k) offerings (i.e. traditional Roth and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance legal services and other addition we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal state and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications merit and business need. Applicants will receive consideration for employment without regard to race ethnicity color religion sex gender identity sexual orientation national origin age disability protected veteran or disabled status or other characteristic protected by applicable federal state or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals Hiring Managers seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigals name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g. fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses with Madrigal misspelled have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to .