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Job Summary
About the position
PhD Position Investigating Mechanisms Controlling the Heartbeat
Using Super-Resolution Microscopy
Applications are invited for a 3-year PhD position evaluating the tiny mechanisms that control cardiomyocyte contraction and thus the heartbeat. The position will be based at the Institute for Experimental Medical Research (IEMR) located at Oslo University Hospital.
IEMR is an innovative and dynamic medical research environment that conducts research focused on understanding the basic mechanisms of cardiac (patho)physiology. With approximately 60 employees and six research groups our expertise spans molecular biology physiology and cardiology. The project will be supervised by Professor William Louch.
Oslo University Hospital is a workplace with great diversity. We believe this is crucial for solving our tasks in the best possible way. We want this diversity to be reflected among the applicants for our positions and we encourage all qualified candidates regardless of background to apply!
Key information
Work tasks
The PhD position will be 3 years in duration and depending on starting date have latest completion of the end of 2028. Funding will be provided by a grant from the Norwegian Association for Public Health.
The heartbeat is generated by the contraction of its muscle each cell this process is initiated by the release of calcium which requires that two types of calcium channels work together. Calcium first enters the cell through L-type calcium channels (LTCCs) in the cells surface membrane and this triggers additional calcium release from channels called Ryanodine Receptors (RyRs). However despite decades of research it remains unclear how the communication between these two channels actually occurs to control the heartbeat. How close do the two channels need to be to each other How many of each channel are activated during the heartbeat Is their communication fine-tuned in times of need and is it disrupted during disease
This project will address these questions by using a new type of super-resolution microscopy (MINFLUX) that has the ability to visualize tiny structures like individual ion channels (LTCCs and RyRs). With these experiments the PhD students work will provide critical new understanding of how the heartbeat is triggered at its very basic level and how this is altered in disease.
Qualifications
We ask all applicants to respond to the qualification requirements. We will not consider applications lacking this information.
- We are looking for talented and highly motivated candidates of all nationalities who have a keen interest in cellular and cardiovascular research
- Applicants must hold a MSc in Biology Biomedical Sciences Engineering Physics or a related field
- Previous experience with light microscopy techniques rodent models and/or programming will be considered an asset
- Fluent oral and written communication skills in English are required
Value will be placed on compatibility of the applicants professional and personal disposition with
strengths in:
- Systematic approach
- Analysis and assessment
- Implementation
- Self development
- Initiative and accountability
Personal qualifications
- Enthusiastic reliable and structured
- Genuine interest in research
- Dedicated and responsible
We offer
- Salary according to agreement
- A stimulating challenging and friendly international working environment with broad expertise
- Technical assistance and training
- Attractive welfare benefits and a generous pension agreement in addition to Oslos family-friendly environment with its rich opportunities for culture and outdoor activities
- We take care of our new employees and support you through teh start-up phase with our central new employee programread more: have welfare offers for our employees e.g. theater tickets company choirs company sport teams etc.
At Oslo University Hospital we provide advanced patient care research experimental treatment teaching and inovation at a high international level. We are therefore the rearguard of all Norway. We need you on the team.
Does this sound like a position for you We look forward to reading your application.
Do you want to know more about us
Read about or work place here:
- Cover letter (statement of motivation summarizing scientific work and research interest)
- CV (summarizing education positions pedagogical experience administrative experience and other qualifying activities)
- Copies of educational certificates (academic transcripts only)
- List of reference persons: 2-3 references (name relation to candidate e-mail and phone number)
The application with attachments must be delivered in our electronic recruiting system. The attachments should be in the form of one or two pdf files that include all requested items.
Foreign applicants are advised to attach an explanation of their Universitys grading system. Please note that all documents should be in English (or a Scandinavian language).
In assessing the applications special emphasis will be placed on the documented academic qualifications in regards to the project description and the candidates motivation and personal suitability. Interviews with the best-qualified candidates will be arranged.
It is expected that the successful candidate will be able to complete the project in the course of the period of employment.
Address: KirkeveienOslo Norway
Contacts
About the employer
Oslo University Hospital is a highly specialised hospital in charge of extensive regional and local hospital assignments and the provision of high quality services for the citizens of Oslo. The hospital also has a nationwide responsibility for a number of national and multi-regional assignments and has several national centres of competence. The hospital is Scandinavias largest and we each year carry out more than 1.2 million patient treatments. Oslo University Hospital is responsible for approximately 50 percent of all medical and healthcare research conducted at Norwegian hospitals and is a significant role player within the education of a large variety of health care personnel. We are an emergency hospital for East and Southern Norway and have national emergency assignments. The hospital has a total budget of NOK 17 billion. More than 20000 employees are engaged with activities at more than 40 different locations.
The University of Oslo is Norways oldest and highest rated institution of research and education with 28 000 students and 7000 employees. Its broad range of academic disciplines and internationally esteemed research communities make UiO an important contributor to society. The Faculty of Medicine was established in 1814 and is the oldest medical faculty in Norway. The Faculty is organized into three basic units and has approximately 1500 employees and about 2000 students. The Institute of Clinical Medicine (Klinmed) is one of three institutes under the Faculty. Klinmed is responsible for the Facultys educational and research activities at Oslo University Hospital and Akershus University Hospital. With about 800 employees spread over approximately 425 man-labour years Klinmed is the universitys largest institute.
Key Skills
- Teacher Coaching
- Public Health
- Google Docs
- Classroom Experience
- Systems Engineering
- Research Experience
- Teaching
- Grant Writing
- Leadership Experience
- Mentoring
- Public Speaking
- Writing Skills
About Company
Oslo University Hospital is a highly specialised hospital in charge of extensive regional and local hospital assignments and the provision of high quality services for the citizens of Oslo. The hospital also has a nationwide responsibility for a number of national and multi-regional a ... View more
