Senior Scientist I (Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research)
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Job Location:
Monthly Salary:
Posted on:
30+ days ago
Vacancies:
1 Vacancy
Job Summary
Union: Non-Union
Number of vacancies: 1
Site: Krembil Brain Institute
Department: Research
Reports to: Research Institute Director
Hours: 37.5 hours per week
Shifts: Day
Status: Permanent Full-time
Closing Date: November 30 2025
Position Summary
The Krembil Brain Institute (KBI) at University Health Network (UHN) a University of Toronto (U of T) teaching hospital is seeking applicants for the Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research. The successful candidate currently holds at minimum a Senior Scientist appointment at the Krembil Brain Institute and must already hold at minimum Associate Professor faculty status at the University of Toronto within the Temerty Faculty of Medicine. The term of the Chair position is 5 years.
The Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research will develop and lead research to explore the fundamental mechanisms of protein misfolding in neurodegeneration and to lead efforts to develop novel therapies. The Chairholder will explore the mechanisms by which proteins especially Tau and a-synuclein misfold and aggregate in the brain as well as how these proteins interact. They will also identify molecular processes that could be targeted using immunotherapy or gene therapy against misfolded or pathogenic proteins to prevent or halt neurodegeneration.
The Chairholder will be encouraged to conduct transdisciplinary research drawing insights from multiple fields such as molecular biology genetics biochemistry neuroimmunology and systems neuroscience and to champion neurodegeneration research in Canada and beyond.
Salary will be commensurate with qualifications and experience.
A complete package MUST include the following elements. Please combine these into a SINGLE file to attach to the application:
- Cover letter
- Curriculum vitae
- Research program proposal (up to 2 pages excluding references)
- Teaching and mentorship statement (1/2 page)
- Equity diversity and inclusion statement (1/2 page)
Duties
- The successful applicant has established and will continue to maintain an original competitive and independently funded research program of international caliber
- Will be expected to teach at the undergraduate and graduate levels
Qualifications :
- Candidates must have a Ph.D. and/or M.D. in a relevant scientific discipline as well as significant postdoctoral research experience and an established record of research excellence
- The successful applicant is appointed as a Senior Scientist at the Krembil Brain Institute at UHN
- Candidates are expected to demonstrate evidence of 1) outstanding peer-reviewed publications in leading journals; 2) successful research funding (peer-reviewed grants fellowships etc.); 3) presentations at significant conferences; and 4) significant leadership experience in directing a research team
Additional Information :
Why join UHN
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts on-site gyms etc.)
Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest however only those selected for further consideration will be contacted.
Remote Work :
No
Employment Type :
Full-time
Union: Non-Union
Number of vacancies: 1
Site: Krembil Brain Institute
Department: Research
Reports to: Research Institute Director
Hours: 37.5 hours per week
Shifts: Day
Status: Permanent Full-time
Closing Date: November 30 2025
Position Summary
The Krembil Brain Institute (KBI) at University Health Network (UHN) a University of Toronto (U of T) teaching hospital is seeking applicants for the Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research. The successful candidate currently holds at minimum a Senior Scientist appointment at the Krembil Brain Institute and must already hold at minimum Associate Professor faculty status at the University of Toronto within the Temerty Faculty of Medicine. The term of the Chair position is 5 years.
The Piyush Kumar and Usha Agarwal Chair in Neurodegenerative Disease Research will develop and lead research to explore the fundamental mechanisms of protein misfolding in neurodegeneration and to lead efforts to develop novel therapies. The Chairholder will explore the mechanisms by which proteins especially Tau and a-synuclein misfold and aggregate in the brain as well as how these proteins interact. They will also identify molecular processes that could be targeted using immunotherapy or gene therapy against misfolded or pathogenic proteins to prevent or halt neurodegeneration.
The Chairholder will be encouraged to conduct transdisciplinary research drawing insights from multiple fields such as molecular biology genetics biochemistry neuroimmunology and systems neuroscience and to champion neurodegeneration research in Canada and beyond.
Salary will be commensurate with qualifications and experience.
A complete package MUST include the following elements. Please combine these into a SINGLE file to attach to the application:
- Cover letter
- Curriculum vitae
- Research program proposal (up to 2 pages excluding references)
- Teaching and mentorship statement (1/2 page)
- Equity diversity and inclusion statement (1/2 page)
Duties
- The successful applicant has established and will continue to maintain an original competitive and independently funded research program of international caliber
- Will be expected to teach at the undergraduate and graduate levels
Qualifications :
- Candidates must have a Ph.D. and/or M.D. in a relevant scientific discipline as well as significant postdoctoral research experience and an established record of research excellence
- The successful applicant is appointed as a Senior Scientist at the Krembil Brain Institute at UHN
- Candidates are expected to demonstrate evidence of 1) outstanding peer-reviewed publications in leading journals; 2) successful research funding (peer-reviewed grants fellowships etc.); 3) presentations at significant conferences; and 4) significant leadership experience in directing a research team
Additional Information :
Why join UHN
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts on-site gyms etc.)
Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest however only those selected for further consideration will be contacted.
Remote Work :
No
Employment Type :
Full-time
Key Skills
- Laboratory Experience
- Machine Learning
- AI
- Bioinformatics
- Biochemistry
- Assays
- Research Experience
- Next Generation Sequencing
- Drug Discovery
- Research & Development
- Natural Language Processing
- Molecular Biology
About Company
The University Health Network, where above all else the needs of patients come first, encompasses Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute and the Michener Institute of Education. The breadth of research, t ... View more
