Clinical Pharmacometrician, Clinical Development

Job Title: Clinical Pharmacometrician Early Clinical Development

Location: Gaithersburg MD US

Introduction to role

Are you ready to follow the science and explore new frontiers in clinical pharmacometrics As a Clinical Pharmacometrician in Early Clinical Development youll dive into the depths of population PK PKPD exposure-response exposure-safety and tumor growth modeling. With the support of our Principal Pharmacometrician and TA lead pharmacometrician youll integrate and analyze data to drive interpretation and decision-making across all phases of clinical development. Are you prepared to make a difference

Accountabilities

Accountable for data integration analysis and reporting of M&S results at the study level
Accountable for executing state-of-the-art M&S techniques with direct value for the project
Contribute M&S activities to influence study designs and go/no go decisions
Development of (mechanistic) drug-disease models to support projects within a specific disease domain
Contribute to regulatory documents and interactions (written)
Presentation of M&S results in internal and external forums
Contribute to internal initiatives to develop the pharmacometric discipline including its processes
Participation in peer review of ongoing activities reports and presentations
Compliance with Good Clinical Practice (GCP) regulations as well as internal/external guidance

Essential Skills/Experience

• Masters degree required PhD degree preferred or equivalent (./Pharm.D.) with relevant 0-3 yrs experience required)

• Training and experience with PK software (NonMEM R SAS Monolix Matlab)

• Demonstrated experiences in pharmacometrics including PK or PKPD

• Strong quantitative skills (e.g. experience in population modeling statistics pharmacology modeling)

• Ability to identify develop and execute clinical Pharmacometric activities at a project level

• Basic oral and written communication skills

Desirable Skills/Experience

• Scientific publishing in the field of pharmacometrics

• Early or late phase clinical development experience/awareness
  

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

At AstraZeneca we are committed to making a difference by fusing data and technology with scientific innovation. Our curiosity and courage drive us to explore new possibilities in treating complex diseases. We work seamlessly as one team leveraging diverse global knowledge to create impactful solutions. With opportunities for continuous learning and growth we push the boundaries of science to deliver life-changing medicines.

Ready to make an impact Apply now and join us on this exciting journey!

The annual base pay (or hourly rate of compensation) for this position ranges 108784.80 - 163177.20 USD Annual. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.