drjobs Bioinformatics Scientist II- Variant Calling

Bioinformatics Scientist II- Variant Calling

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Job Location drjobs

Palo Alto, CA - USA

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

About the Role:

The Bioinformatics Scientist II will join an interdisciplinary team working with an unprecedented set of clinical DNA whole genome and exome sequence data and multiple epigenetic data types produced by novel R&D pipelines at Guardant Health. The scope of this project provides unique opportunities for developing and learning novel analytical methods for DNA sequencing data including cell free DNA-based genomic and methylation data integrated with epigenetic data sets.

Essential Duties and Responsibilities:

  • Work with large complex data sets. Tend to non-routine analysis problems applying deep epigenetic knowledge to conduct end-to-end analysis of epigenetic cell-free nucleic acid NGS data.
  • Development continuous improvement and validations of biomarkers for Guardant Health oncology products. 
  • Develop or apply statistical methods and procedures to evaluate and validate Guardant Health technologies.
  • Work with the Technology Development team to develop and analyze verification and validation experiments as part of regulatory submissions.
  • Provide analytic support on individual samples and research activities.
  • Develop scripts for research and development activities and leverage cutting edge AI methods to continuously improve efficiency.
  • Communicate research results through presentations and project reports as well as scientific publications.

Qualifications :

  • PhD in Bioinformatics Statistics Computational biology Genomics or related quantitative fields and a minimum of 2-5 years related experience; may include post-doctoral experience.
  • Deep understanding of library preparation methods used to generate next-generation sequencing data including whole-genome and methylation sequencing targeted sequencing and RNA-seq
  • Demonstrated experience in developing methods for analysis of experimental data in genomics and next-generation sequencing under the context of product development
  • Strong knowledge of statistics and computational biology algorithms for genomic analysis (including statistical methods employed in analytical validation) and cancer genomics (alignment variant calling general multivariate statistical inference)
  • Excellent communication and teamwork skills to foster a highly collaborative environment working with both experimental and computational scientists

Must have:

  • 2 years of variant calling experience


Additional Information :

Hybrid Work Model: At Guardant Health we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays Tuesdays and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $120280 to $165410. The range does not include benefits and if applicable bonus commission or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto CA or Redwood City CA the base salary range for this full-time position is $141500 to $194600. The range does not include benefits and if applicable bonus commission or equity.

Within the range individual pay is determined by work location and additional factors including but not limited to job-related skills experience and relevant education or training. If you are selected to move forward the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however there may be exposure to high noise levels fumes and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities long-term conditions mental health conditions or sincerely held religious beliefs. If you need support please reach out to 

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health Inc. and how it is used please review our Privacy Notice for Job Applicants.

Please visit our career page at:  Work :

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Employment Type :

Full-time

Employment Type

Full-time

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