Research Intern (Downstream Processing) - Onsite Marlborough, MA
Research Intern (Downstream Processing) - Onsite Marlborough, MA
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1 Vacancy
Job Description
Hands on position starting September 2025 for a minimum of six months up to a maximum of ten months
Onsite at our Marlborough MA site
In the Research Intern role you will serve as a critical contributor to the development and integration of Sartorius emerging technologies for characterization and purification of different types of nanoparticles such as extracellular vesicles and viral vectors. These leading-edge platforms will be utilized in basic research as well as the pharmaceutical and biotechnology industries.
What you will accomplish together with us
Execute Purification Protocols: Perform purification of EVs and viral vectors using TFF systems (hollow fiber and/or flat sheet) and various chromatography modalities (e.g. ion exchange size exclusion affinity).
Optimize Unit Operations: Assist in the design and optimization of downstream steps to improve product yield purity and scalability.System Operation and Maintenance: Operate and maintain TFF and chromatography systems (e.g. AKTA or equivalent) including set-up cleaning and troubleshooting.
Sample Handling and Quantification: Prepare and process samples following SOPs. Quantify particles using orthogonal methods such as NTA qPCR protein assays and total RNA analysis.
Process Monitoring and Data Recording: Monitor and document key parameters (e.g. transmembrane pressure flux recovery) during TFF runs. Maintain detailed lab notebooks and process logs.
Analytical Support: Support integration of downstream data with analytical assays (e.g. flow cytometry SEC-MALS SDS-PAGE) for process characterization.
Collaborative Work: Interact regularly with upstream analytical and formulation teams to align on process goals and transfer knowledge.
Safety and Compliance: Follow laboratory safety protocols and ensure compliance with quality standards and experimental reproducibility.
What will convince us
Education:
- PhD candidate (or recent graduate) in Bioengineering or closely related discipline with formal education and experience with extracellular vesicles characterization and purification.
Experience:
Hands-on experience with TFF systems (lab or pilot scale) for nanoparticle or biologics concentration and diafiltration.
Practical knowledge of chromatography techniques such as SEC IEX or affinity purification.
Familiarity with nanoparticle systems such as EVs viral vectors (e.g. AAV lentivirus) or LNPs.
Comfortable working in a wet lab environment with complex biological samples.
Strong documentation and organizational skills; experience with SOPs and batch records is a plus.
Experience with analytical tools (e.g. NTA BCA qPCR HPLC or SEC-MALS) is highly desirable
- Identification with our core values: Sustainability Openness Enjoyment
Compensation is up to $30 hr.
What We Offer
As a growing global life science company with our stock listed on the German DAX and TecDAX Sartorius offers a wide range of benefits:
Personal and Professional Development: Mentoring leadership programs internal seminar offerings
Making an Impact Right from the Start: Comprehensive onboarding including a virtual online platform
Welcoming Culture: Mutual support team spirit and international collaboration; communities on numerous topics such as Coaching Agile Working and a Businesswomens Network
Intelligent Working Environment: Working in smart buildings with the latest technology and equipment.
Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex national origin age protected veteran status disability or based on status in any other protected group of class.
Please view equal employment opportunity posters provided by OFCCP here.
Sartorius is part of the solution in the fight against cancer dementia and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster so that new therapeutics can reach patients worldwide. We look for ambitious team players and creative minds who want to contribute to this goal and advance their careers in a dynamic global environment. Join our global team and become part of the solution. We are looking forward to receiving your application.
We look forward to receiving your application.
you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at
Sartorius is an equal opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex national origin age protected veteran status or disability or based on status in any other protected group of class.
If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening. You can request reasonable accommodation by e-mail at
About Sartorius
Sartorius is part of the solution in the fight against cancer dementia and many other diseases. Our technologies help translate scientific discoveries into real-world medicine faster so that new therapeutics can reach patients worldwide.
We look for ambitious team players and creative minds who want to contribute to this goal and advance their careers in a dynamic global environment.
Join our global team and become part of the solution. We are looking forward to receiving your application.
Experience:
Intern
Employment Type
Full-Time
Key Skills
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