Protein Expression Scientist
Protein Expression Scientist
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Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
- Perform largescale (up to 10 L) expression of recombinant proteins and viruslike particles (VLPs) by transient transfection of suspension mammalian cells across multiple expression systems including shake flask and WAVE bioreactor technology
- Optimize expression conditions for challenging proteins including multimeric proteins to improve yield and quality
- Maintain and expand mammalian cell lines ensuring proper cell density viability and sterility
- Operate and maintain cell culture analyzers including the BioProfile FLEX analyzer to monitor cell culture health and productivity
- Conduct protein characterization using techniques such as SDSPAGE Western blot analysis and UVVIS spectroscopy
- Troubleshoot and resolve issues related to protein expression cell culture and equipment operation
- Maintain detailed records of experiments protocols and results under company policies and regulatory requirements
- Work closely with a lead scientist in the expression group and coordinate with the protein purification and characterization groups in the facility
- Contribute to the development and optimization of new protein expression protocols and techniques
- Participate in team meetings and present findings to colleagues and management
- Ensure compliance with all safety protocols and regulations in the laboratory environment
- Assist in training junior team members on protein expression techniques and equipment usage
Qualifications :
Minimum Qualifications:
- MS in biology biochemistry or related scientific field. Or BS in biology biochemistry or related scientific field with 2 or more years of relevant postgraduation work experience in a scientific setting with preference given to industrial experience
- Authorization to work in the United States indefinitely without restriction or sponsorship
Preferred Qualifications:
- Experience with largescale (up to 10L) suspension mammalian cell cultures and bioreactor technology including WAVE bioreactor systems
- Proficiency in cell culture techniques including sterile aseptic technique cell passaging counting and using cell culture analyzers (e.g. BioProfile FLEX analyzer)
- Experience with recombinant protein expression by transient transfection of mammalian cells including optimization for challenging proteins
- Expertise in protein characterization techniques such as SDSPAGE Western blot analysis and UVVIS spectroscopy
Additional Information :
This position is FullTime Monday Friday 9:00 a.m. 5:00 p.m. with overtime as needed and the potential for some off shift hours as dependent on project. Candidates currently living within a commutable distance of West Point PA are encouraged to apply.
- Excellent full time benefits including comprehensive medical coverage dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Remote Work :
No
Employment Type :
Fulltime
Employment Type
Full-time
