Bioreactor Modelling Scientist / Engineer (Singapore)

Animal Alternative Technologies (AAT) is a recently founded biotechnology B2B start-up based in the University of Cambridge. We are engineering a scalable, end-to-end Cultured Meat production system, including bioprocesses, enabling technologies, software, hardware and raw materials to empower food producers all over the world to make their own cultivated meats tailored to local tastes and desired specifications. Our mission is to democratize access to sustainable food and tackle some of the world's biggest sustainability and food security challenges.

Tasks

We are a rapidly growing cultured meat start-up looking for a Computational Modelling Scientist/Engineer with experience in the computational modelling of cell growth and metabolism AND bioreactors (including heat and mass transfer processes, scale-up as well as Computational Fluid Dynamics - CFD) to join our core team! You will be flexible and able to handle rapidly changing priorities on various cross-functional projects. You are an independent problem solver who enjoys working in fast-paced environments. As a senior scientist and early team member, you will play a pivotal role in shaping our technology and the company's direction.

Responsibilities:

• Mammalian cell growth modelling
• Mammalian cell metabolic modelling (e.g. FBA)
• Computational Fluid Dynamics (CFD)
• Bioreactor modelling (including scale-up, scale-down, heat and mass transfer processes, etc.) to inform bioreactor design and optimization
• Bioprocess modelling
• Work hand in hand with scientists at the bench, to ensure a close coupling between experimental and computational approaches and improve data-gathering methods.
• Planning, efficient execution, comprehensive analysis, and presentation of data.
• Potentially building predictive models (including Machine Learning models).
• Coordination of engineering projects.
• Working as a self-starter and problem solver, willing to jump in wherever you may be needed.

Requirements

Essential:

• Minimum Bachelor s degree in a relevant subject, such as Computer Science, Biotechnology, Biochemical Engineering, Mechanical Engineering, Chemical Engineering, or Bioengineering.
• PhD or at least 3 years of relevant work experience beyond a Bachelor's or Master's
• High competency with one or more modelling software/ programming languages such as Python, MATLAB, COMSOL, ANSYS, etc.
• Bioreactor modelling (including heat and mass transfer processes, etc.) to inform bioreactor design and optimization
• Computational Fluid Dynamics (CFD)
• Cell growth, metabolic and/or gene network modelling (ideally within bioreactors)
• Building mathematical optimization models (Multi-Objective Optimization)
• Strong technical skills in data cleaning, mining, manipulation, and analysis

Desirable (at least 4 or more):

• Design, implementation, and evaluation of machine learning models (ideally in biology)
• Familiarity with software development practices
• Strong understanding of different ML approaches (including deep learning)
• Metamodelling and hybrid models
• Generate insights, tools and applications from large volumes of data
• Computational Fluid Dynamics- modelling of a stirred tank (bioreactor)
• Modelling of a fluid flow through porous media
• Mammalian cell growth, metabolic and/or gene network modelling
• Bioreactor design and development (driven by modelling)
• Systems modelling
• Bioprocess modelling
• Bioinformatics
• Programming of PID controllers, arduinos, and other hardware
• Development of bioreactor control software
• Validation of models through wet-lab work, including cell culture (ideally adherent mammalian cells)
• Operation and validation of bioreactors for cells
• Scale-up of bioreactors
• PhD in a relevant subject.
• Senior applicants with over 5-10 years of experience are welcome and will have the opportunity to lead a small team.

Benefits

• Competitive salary and stock options.
• 30 days holiday and pension plan.
• Flexible location.
• Potential for excellent career progression as part a multi-disciplinary team, all leaders in their fields.
• Contribute to the development of cultured meat using cutting-edge technologies to help tackle sustainability and food security challenges.
• We are backed by the Cambridge Judge Business School and the world's leading food-tech VCs.

AAT is an Equal Opportunities Employer.
We are committed to creating inclusive teams and providing a work environment that allows all to be themselves.

Please attach your CV and a cover letter. We look forward to hearing from you!