Validation Engineer
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Job Description
About PSC Biotech Ltd
Who we are?
PSC Biotech is a leading Biotech Consultancy firm founded in 1996, headquartered in Pomona, California, USA, with Global operations in Ireland, India, Singapore, Australia and the US, serving 350 clients in more than 23 countries worldwide. We provide cloud-based software solutions for Quality Management and Regulatory Inspections, pharmaceuticals contract manufacturing professionals, and metrology services to our clients.
Role Functions
Bring energy, knowledge, innovation to carry out the following:
Design/Author/Review/Approve/Execute qualification/validation documentation and cycle development studies in line with the standard approval process.
Design/Author/Review/Approve/Execute Execution/development of change controls.
Resolving technical issues encountered during study execution.
Engagement with Production, Maintenance and Quality representatives in the assigned area of operations during execution of Cycle Development & Performance Qualification activities.
Technical input into quality notification by authoring/reviewing/approving investigations.
Perform root cause analysis of system failures, substandard performance, using standard tools and methods, to resolve machine and system issues.
Support continuous improvement through Lean Six Sigma methodologies.
Serve as validation representative for cross functional projects and represent the validation team at global technical forums
Drive compliance of Global Policies, Procedures and Guidelines, regulatory requirements and execute current Good manufacturing Practices (cGMP) in the performance of day-to-day activities and all applicable job functions, ensuring consideration of the impact on GMP and compliance and decisions made.
Accountable for compliance via documentation completion, risk assessments, closing out corrective actions, participation in audits and inspections and proactively highlighting any issues around compliance
Supporting regulatory audits and submissions as required.
Work collaboratively to drive a safe and compliant culture in Carlow.
Requirements
What skills you will need:
In order to excel in this role, you will more than likely have considerable experience in a comparable role, with experience operating as individual contributor adding value to the business in a GMP manufacturing setting, as well as the following qualifications/skills:
Relevant technical qualification(s) in Applied Pharmaceutical / Biological / Chemical sciences or applied Technical / Engineering qualification, the successful candidate will also have a proven track record in delivering excellence.
Knowledge of HVAC systems
Knowledge of Isolator VHP qualification
Knowledge of Sterilisation processes for Isolators
Thermal mapping skills
Exception / Deviation Management and Change Control.
Demonstratable experience of leading technical related projects.
Knowledge of process monitoring systems, automation systems (DeltaV), operational intelligence & data systems (Pi System) within a GMP manufacturing environment would be beneficial and desirable
Evidence of continuous professional development is desirable.
Knowledge of regulatory/code requirements to Irish, European and International Codes, Standards and Practices.
Ability to analyse and interpret complex data, and link to equipment performance and out of specification findings as appropriate.
Report, standards, policy writing skills required.
Equipment and process validation.
Sterile Fill-Finish processes and equipment.
Proficiency in Microsoft Office and job-related computer applications required
Excellent communication, presentation and interpersonal skills, to interface effectively with all levels of colleagues and with external customers in a team orientated manner.
Knowledge and experience of the below areas will be considered advantageous
Equipment Periodic Validation
Equipment Validation Lifecycle
Project Management Skills/Qualification
Filter Validation & Container Closure Validation
Autoclave/SIP Sterilisation Validation
Dry Heat Sterilisation
Controlled Temperature Units/Equipment Qualification
Vial and Syringe Processing Technologies
What skills you will need: In order to excel in this role, you will more than likely have considerable experience in a comparable role, with experience operating as individual contributor adding value to the business in a GMP manufacturing setting, as well as the following qualifications/skills: Relevant technical qualification(s) in Applied Pharmaceutical / Biological / Chemical sciences or applied Technical / Engineering qualification, the successful candidate will also have a proven track record in delivering excellence. Knowledge of HVAC systems Knowledge of Isolator VHP qualification Knowledge of Sterilisation processes for Isolators Thermal mapping skills Exception / Deviation Management and Change Control. Demonstratable experience of leading technical related projects. Knowledge of process monitoring systems, automation systems (DeltaV), operational intelligence & data systems (Pi System) within a GMP manufacturing environment would be beneficial and desirable Evidence of continuous professional development is desirable. Knowledge of regulatory/code requirements to Irish, European and International Codes, Standards and Practices. Ability to analyse and interpret complex data, and link to equipment performance and out of specification findings as appropriate. Report, standards, policy writing skills required. Equipment and process validation. Sterile Fill-Finish processes and equipment. Proficiency in Microsoft Office and job-related computer applications required Excellent communication, presentation and interpersonal skills, to interface effectively with all levels of colleagues and with external customers in a team orientated manner. Knowledge and experience of the below areas will be considered advantageous Equipment Periodic Validation Equipment Validation Lifecycle Project Management Skills/Qualification Filter Validation & Container Closure Validation Autoclave/SIP Sterilisation Validation Dry Heat Sterilisation Controlled Temperature Units/Equipment Qualification Vial and Syringe Processing Technologies The successful candidate will be required to work both independently and in a cross-functional team to accomplish validation project objectives. Works with moderate work direction and is skilled and knowledgeable to the position. Relevant technical qualification(s) in Applied Pharmaceutical / Biological / Chemical sciences or applied Technical / Engineering qualification, the successful candidate will also have a proven track record in delivering excellence.
Employment Type
Full Time
Key Skills
