Bamu Damaris

Bamu Damaris

Bioinformatics Data Scientist
Germany
English, German, French

نبذة عني

Bioinformatics scientist with 4+ years of experience designing, deploying, and supporting scalable NGS and multi-omics analysis pipelines across clinical and research datasets. Skilled in Python, R, Snakemake, SQL, Linux…

الخبرة

Freelance Genomic and NGS Analyst

Independent Consulting, Germany
May 2025 - حتى الآن · 1 سنة 2 أشهر

Deliver end-to-end genomic and transcriptomic analyses for research and clinical clients using reproducible, scalable workflows.
Scope and communicate analysis plans to non-expert stakeholders including clinicians and principal investigators.
Review and optimise existing client pipelines.
Provide technical training and mentoring to early-career scientists on bioinformatics best practices and reproducible research methods.

Freelance Genomic and NGS Analyst

Independent Consulting, Germany
May 2025 - حتى الآن · 1 سنة 2 أشهر

Deliver end-to-end genomic and transcriptomic analyses for research and clinical clients using reproducible, scalable workflows., Scope and communicate analysis plans to non-expert stakeholders including clinicians and principal investigators; review and optimise existing client pipelines., Provide technical training and mentoring to early-career scientists on bioinformatics best practices and reproducible research methods.

Computational Biologist

Institute of Molecular Bacteriology, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany
Oct 2020 - Feb 2025 · 4 سنوات 4 أشهر

Designed and deployed scalable data pipelines in Python, R and Snakemake integrating genomic, transcriptomic, and phenotypic data across 2,000+ clinical isolates.
Co-developed an open-source bacterial Genome Wide Association Study (GWAS) platform deployed on HPC and AWS and adopted by external research groups.
Performed phylogenetic reconstruction and bacterial GWAS across 430+ commensal Escherichia coli, identifying genetic variants associated with suppression of multidrug-resistant strains.
Identified transcriptional mechanisms underlying bacterial killing and biofilm inhibition in Pseudomonas aeruginosa via RNA-seq analysis, informing antimicrobial peptide discovery.
Validated computational predictions through reporter assays and expression profiling, confirming cis-regulatory variant effects on gene expression and resistance phenotypes.
Delivered analytical reports and visualisations to senior researchers, supporting strategic project decisions.
Mentored graduate students in reproducible bioinformatics.

Computational Biologist

Institute of Molecular Bacteriology, TWINCORE Centre for Experimental and Clinical Infection Research, Hannover, Germany
Oct 2020 - Feb 2025 · 4 سنوات 4 أشهر

Designed and deployed scalable data pipelines in Python, R and Snakemake integrating genomic, transcriptomic, and phenotypic data across 2,000+ clinical isolates., Co-developed an open-source bacterial Genome Wide Association Study (GWAS) platform deployed on HPC and AWS and adopted by external research groups. Platform published in Microbial Genomics, 2025., Performed phylogenetic reconstruction and bacterial GWAS across 430+ commensal Escherichia coli, identifying genetic variants associated with suppression of multidrug-resistant strains. Findings published in Nature Communications, 2025., Identified transcriptional mechanisms underlying bacterial killing and biofilm inhibition in Pseudomonas aeruginosa via RNA-seq analysis, informing antimicrobial peptide discovery., Validated computational predictions through reporter assays and expression profiling, confirming cis-regulatory variant effects on gene expression and resistance phenotypes., Delivered analytical reports and visualisations to senior researchers, supporting strategic project decisions; mentored graduate students in reproducible bioinformatics.

Research Assistant

INRAE - National Research Institute for Agriculture, Food and Environment, France
Jan 2020 - Jun 2020 · 5 أشهر

Analysed RNA-seq data from pathogen-stimulated macrophages, producing troubleshooting reports that guided experimental design iterations.
Executed immune-stimulation assays using Streptococcus uberis, E. coli LPS, and IFNy stimuli.
Performed multicolour flow cytometry and RT-qPCR to characterise immune activation states and cytokine expression dynamics.

Research Assistant

INRAE - National Research Institute for Agriculture, Food and Environment, France
Jan 2020 - Jun 2020 · 5 أشهر

Analysed RNA-seq data from pathogen-stimulated macrophages, producing troubleshooting reports that guided experimental design iterations., Executed immune-stimulation assays using Streptococcus uberis, E. coli LPS, and IFNy stimuli; performed multicolour flow cytometry and RT-qPCR to characterise immune activation states and cytokine expression dynamics.

Project Manager, Clinical Research

Integrated Health Organization, Cameroon
Jul 2017 - Dec 2019 · 2 سنوات 5 أشهر

Directed HIV and HBV clinical screening campaigns reaching 500+ individuals.
Managed end-to-end data collection, quality assurance, and stakeholder reporting.
Implemented SOPs for data handling and verification.
Trained and supervised field staff.
Liaised between clinical teams and senior management to ensure operational continuity.

Project Manager, Clinical Research

Integrated Health Organization, Cameroon
Jul 2017 - Dec 2019 · 2 سنوات 5 أشهر

Directed HIV and HBV clinical screening campaigns reaching 500+ individuals; managed end-to-end data collection, quality assurance, and stakeholder reporting., Implemented SOPs for data handling and verification; trained and supervised field staff; liaised between clinical teams and senior management to ensure operational continuity.

المهارات

بايثون (لغة برمجة) اختبار الإنزيم المرتبط المقايس تفاعل البوليميراز المتسلسل NGS analysis bacterial GWAS variant calling and annotation pangenome analysis RNA-seq phylogenetics metagenomics R SQL Bash Snakemake Git Unix/Linux Slurm AWS (EC2 S3) high-performance computing (HPC) bacterial culture cell culture flow cytometry RT-qPCR nucleic acid extraction molecular cloning assay support project management stakeholder reporting mentoring and training cross-functional collaboration SOP development AWS EC2 S3 HPC variant calling annotation large-scale data integration transcriptomics clinical isolate analysis multi-omic pipeline development mentoring training
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