حول Bicycle Therapeutics
Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating zelenectide pevedotin (formerly BT8009), a Bicycle® Toxin Conjugate (BTC®) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC molecule targeting EphA2, a historically undruggable target; and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle® Radio Conjugates (BRC™) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle® technology to develop therapies for diseases beyond oncology.
Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA USA
Culture is key and all Bicycle employees actively embrace and role model our company values:
- We are Adventurous. We believe it’s the way to deliver extraordinary results for our patients.
- We are Dedicated to our Mission. You can’t change the world if you don’t have determination.
- We are One Team. We only succeed when we work together.
5 فرصة عمل في Bicycle Therapeutics
Senior Director, Head Of Clinical Science
Bicycle Therapeutics is seeking a motivated professional with oncology experience to serve as Senior Director and Head of Clinical Science in its Cambridge Massachusetts office. This role sits within a growing clinical department working to advance highly novel Bicycle (bi-cyclic pept المزيد...
Associate Director, Information And Cyber Security
We have an exciting new opportunity for an experienced Information and Cyber Security Manager to join our growing team. In this role you will operate and continuously improve the organisations cyber and information security capabilities. Working closely across our business areas you w المزيد...
1st/2nd Line It Support Engineer - 6 Month Ftc
Role purposeAs our company expands we have created an exciting new opportunity for a 1st / 2nd Line IT Support Engineer to join our UK team at Granta Park near Cambridge.You will support the IT systems throughout the organisation. These include setup and maintenance of desktop compute المزيد...
Senior Director, Head Of Clinical Science
Bicycle Therapeutics is seeking a motivated professional with oncology experience to serve as Senior Director and Head of Clinical Science in its Cambridge Massachusetts office. This role sits within a growing clinical department working to advance highly novel Bicycle (bi-cyclic pept المزيد...
Quality Control And Validation Manager
Reporting to the Senior Director CMC Quality you will provide expert advice to the Bicycle CMC team on the requirements for environmental monitoring microbiology sampling and testing for aseptic drug products. You will work closely with the Analytical Sciences team and will be account المزيد...
