Scientist (Lung BiologyLung Organoids)
South San Francisco, CA - USA
Job Summary
Our client a world leader in biotechnology and gene therapy is looking for an Scientist based in South San Francisco CA.
Job Duration: Long Term Contract (Possibility Of Extension)
Pay Rate : $57/hr on W2
Company Benefits: Medical Dental Vision Paid Sick leave 401K
Seeking a highly motivated Scientist to develop characterize and qualify advanced human lung complex in vitro models to support drug discovery disease modeling and translational safety assessment. This fully onsite role will work with innovative systems including lung organoids air-liquid interface (ALI) cultures co-culture models and lung-on-a-chip/microphysiological platforms.
Key Responsibilities
- Develop optimize qualify and implement human lung complex in vitro models for drug development and safety assessment.
- Culture and characterize primary lung cells cell lines organoids ALI cultures and microphysiological systems.
- Design and execute model characterization studies assessing cell viability morphology barrier integrity and functional responses.
- Apply techniques including qRT-PCR RNA-seq proteomics immunofluorescence confocal microscopy live-cell/time-lapse imaging high-content imaging and permeability/TEER assays.
- Analyze complex datasets and communicate scientific findings to cross-functional teams.
- Troubleshoot and optimize experimental methods and protocols.
- Maintain accurate electronic documentation and contribute to study reports safety assessments presentations and publications.
- Collaborate with teams across Research Development Sciences and Translational Medicine.
Required Qualifications
- PhD in Bioengineering Cell Biology Molecular Biology Toxicology or a related field.
- 05 years of post-PhD research experience in academia or industry.
- Hands-on experience with lung biology primary lung cells and/or relevant cell lines.
- Experience developing or applying lung organoids ALI cultures co-culture systems microfluidic platforms or organ-on-a-chip models.
- Strong experimental design troubleshooting and method development skills.
- Experience with advanced molecular imaging and functional assay techniques.
- Strong data analysis scientific communication documentation and cross-functional collaboration skills.
Preferred Qualifications
- Experience in lung biology and immunology.
- Proficiency in Python and/or MATLAB for image processing algorithm development or large-scale data analysis.
If interested please send us your updated resume at
Required Skills:
lung organoid* OR airway organoid* OR alveolar organoid* OR lung-on-a-chip OR respiratory* OR pulmonary