Research Associate, Platform Technology
Cambridge, MA - USA
Job Summary
About Us
Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets mechanisms and therapeutics inaccessible through traditional methods. With expertise spanning machine learning bioinformatics data science engineering and drug development our multidisciplinary team in Toronto and Cambridge MA is revolutionizing how new medicines are created.
Opportunity
We are looking for a passionate and detail-oriented Research Associate to become an integral part of our Platform Technology team. This is an opportunity to contribute hands-on to an AI-driven drug discovery platform generating the experimental data that directly informs the biological models powering our therapeutic pipeline. You will bring scientific curiosity and rigor to the bench supporting the execution of molecular and sequencing-based assays that our computational and therapeutic teams rely on to advance program goals.
This role offers early-career professionals a meaningful foothold in a cross functional discovery environment with exposure to cutting-edge technologies spanning NGS workflows liquid handling automation and diverse RNA therapeutic modalities including ADAR editing ASOs siRNAs and mRNAs. If you are eager to develop technical breadth while contributing to work that has real therapeutic impact we encourage you to apply.
Key Responsibilities
- Execute amplicon sequencing workflows including NGS library preparation and targeted sequencing under the guidance of senior team members to support the evaluation of RNA therapeutic candidates.
- Carry out library QC using tools such as TapeStation Qubit and qPCR flagging workflow bottlenecks to ensure high-quality datasets for downstream computational analysis.
- Operate sequencing instruments such as the Illumina NextSeq including run setup and routine troubleshooting with increasing independence over time.
- Perform routine molecular biology techniques including PCR qPCR/ddPCR and nucleic acid extractions from a variety of cell types and tissues.
- Assist in running automated workflows on liquid handling platforms (e.g. Hamilton STAR Agilent Bravo Beckman Echo) to support scaling of discovery and screening activities.
- Maintain accurate and thorough documentation of experimental plans results SOPs and troubleshooting steps within an electronic lab notebook (ELN).
- Contribute to team meetings and share experimental results and assay updates with immediate project collaborators.
Basic Qualifications
- BS in Molecular Biology Genetics Genomics Biotechnology Biochemistry or a related discipline with 13 years of relevant industry or research experience (including internships or postgraduate research).
- Foundational knowledge of molecular and cell biology principles.
- Some hands-on exposure to amplicon sequencing or other targeted NGS workflows; broader NGS experience is also welcomed.
- Experience with nucleic acid extraction quantitation and standard molecular biology techniques such as PCR qPCR or d(d)PCR gel electrophoresis.
- Strong attention to detail and commitment to rigorous reproducible lab work.
- Ability to work both independently and collaboratively in a team-oriented environment.
Preferred Qualifications
- Proficiency with liquid handling platforms such as Hamilton Beckman or Bravo.
- Working familiarity with RNA therapeutic modalities such as ADAR editing ASOs siRNAs or mRNA.
- Experience with mammalian cell culture including transfection-based assays.
- Prior exposure to a biotechnology pharmaceutical or platform-driven research environment.
What We Offer
- A collaborative and innovative environment at the frontier of computational biology machine learning and drug discovery.
- Highly competitive compensation including meaningful stock ownership.
- Comprehensive benefits - including health vision and dental coverage for employees and families employee and family assistance program.
- Flexible work environment - including flexible hours extended long weekends holiday shutdown unlimited personal days.
- Maternity and parental leave top-up coverage as well as new parent paid time off.
- Focus on learning and growth for all employees - learning and development budget & lunch and learns.
- Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development and in Kendall Square Cambridge Mass. - a global center of biotechnology and life sciences.
Deep Genomics encourages applications from all backgrounds who seek the opportunity to build the worlds leading AI-driven genetic medicine company.
If you have a disability or special need accommodation is available on request for candidates taking part in all aspects of the selection process.
*This posting reflects a current vacancy.
We offer competitive compensation aligned with local market benchmarks. The salary range for this role is $75000 - $90000 and reflects Cambridge USA-based roles; compensation may differ for Canada-based candidates.
We may use artificial intelligence (AI) tools to support parts of the hiring process such as reviewing applications analyzing resumes or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed please contact us.
Required Experience:
IC
About Company
Revolutions in AI, biology and automation are enabling a new approach to medicine. Deep Genomics is at the forefront.