Principal, Enterprise AI Platform & Strategy | Onsite San Diego HQ

Neurocrine Biosciencesis a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering developing and commercializing life-changing treatments for patients with under-addressed neurological psychiatric endocrine and immunological disorders. The companys diverse portfolio includes FDA-approved treatments for tardive dyskinesia chorea associated with Huntingtons disease classic congenital adrenal hyperplasia hyperphagia in Prader-Willi syndrome endometriosis* and uterine fibroids* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information visit and follow the company onLinkedInX Facebook and YouTube. (*in collaboration with AbbVie)

The Principal IT Engineering Enablement - AI Data Platforms leads enterprise-wide initiatives that define deliver and mature Neurocrines core AI and machine learning platforms. This role combines technical program leadership platform product management and strategic advisory responsibilities to accelerate enterprise adoption of secure scalable and governed AI capabilities. This role partners with Engineering Data Cybersecurity Tech Enablement & Adoption Compliance and business stakeholders to architect platform strategy own the AI services roadmap and orchestrate multi-team execution across complex workstreams. Acting as the organizations primary technical AI subject-matter expert this role drives evaluation of emerging models and technologies ensures alignment to Responsible AI principles and shapes the long-term platform foundation that enables advanced analytics automation and AI-powered applications across Neurocrine.

AI Platform Leadership & Product Ownership

• Owns the strategy roadmap and lifecycle for Neurocrines AI/ML platformsincluding model orchestration RAG pipelines embeddings services prompt governance vector search and model performance monitoring.

• Leads evaluation selection and integration of foundation models third-party AI services and emerging technologies to support enterprise AI use cases.

• Defines platform requirements success metrics technical capabilities and prioritization aligned with business value and risk considerations.

• Develops ROI models for AI use cases and builds executive presentations and updates

Enterprise AI Strategy & Advisory

• Serves as the companys primary AI technical SME advising leadership and cross-functional teams on AI feasibility solution patterns risks and architectural alignment.

• Partners with business units to shape AI concepts into actionable initiatives ensuring platform capabilities and governance frameworks are consistently applied.

• Identifies new opportunities for scalable AI adoption across functions proactively recommending platform enhancements and enterprise best practices.

Responsible AI Governance & Compliance

• Leads the development and ongoing stewardship of Neurocrines Responsible AI governance framework including council facilitation policy creation risk assessments and guardrails for safe and compliant use of AI technologies.

• Partners with Legal Cybersecurity Data Privacy Tech Enablement & Adoption and Compliance to ensure platform standards meet regulatory ethical and organizational requirements.

• Defines operational readiness and auditability criteria for AI-enabled solutions across the enterprise.

Cross-Functional Program Execution

• Drives the end-to-end execution of AI and platform initiativesrequirements dependency management engineering coordination release readiness and enterprise rollout.

• Orchestrates work across engineering data cybersecurity infrastructure and product teams to deliver integrated scalable and secure platform capabilities.

• Implements and reinforces Agile/Scrum practices to improve transparency delivery velocity and alignment across multi-team programs.

• Identifies and mitigates platform bottlenecks or risks related to scalability security cost or developer experience.

• Continuously evaluates industry trends to recommend platform evolutions that improve long-term sustainability and enterprise value.

Platform Health Telemetry & Continuous Improvement

• Establishes and monitors platform KPIsincluding availability performance adoption SLOs usage patterns and business impactto guide roadmap and operational improvements. Key areas include:

  • Business impact (time saved revenue uplift cycle time reduction etc.)

  • Quality of Response (Accuracy hallucination rate latency quality etc.)

  • Management of usage and tokenization optimization

• Identifies and mitigates platform bottlenecks or risks related to scalability security cost or developer experience.

• Continuously evaluates industry trends to recommend platform evolutions that improve long-term sustainability and enterprise value.

Collaboration With Technology Enablement & Adoption

• Partners closely with the Technical Enablement & Adoption Manager to ensure consistent onboarding training and communication for new AI capabilities.

• Contributes subject-matter expertise to enablement content adoption campaigns and enterprise trainingwithout serving as the primary owner of these functions.

Neurocrine Biosciences is an EEO/Disability/Vets employer.

We are committed to building a workplace of belonging respect and empowerment and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications dont line up to exactly what we have outlined in the job description.

The annual base salary we reasonably expect to pay is $132700.00-$182000.00. Individual pay decisions depend on various factors such as primary work location complexity and responsibility of role job duties/requirements and relevant experience and addition this position offers an annual bonus with a target of 30% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match) paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans.