Laboratory Automation Engineer

Colossal is seeking a Lab Automation Engineer to join our laboratory operations team to design develop test and maintain automated systems associated with cell and molecular biology workflows. The successful candidate will support the day-to-day operation maintenance troubleshooting and optimization of automated laboratory instrumentation and integrated automation systems. This individual will work closely with scientists and cross-functional teams to ensure reliable laboratory operations and support automation-driven workflows. The ideal candidate will have hands-on experience with laboratory automation platforms instrumentation support software-driven workflows equipment validation and troubleshooting of automated laboratory instruments along with a strong interest in process improvement and operational efficiency.

This position contributes to a fast-paced and dynamic program and reports to the Director of Lab Operations.

*This position is a full time role in-person at Colossal HQ in Dallas TX. It requires a flexible schedule including some early/late hours and weekend work depending on scientific team needs and required equipment troubleshooting.

Duties and Responsibilities

• Develop and maintain automation methods using laboratory control platforms such as Hamilton Venus/Revolution and HighRes Cellario schedulers.
• Provide hands-on support consumable ordering & restocking troubleshooting and maintenance for automated laboratory instrumentation and integrated automation systems to ensure reliable day-to-day operations.
• Diagnose and resolve complex mechanical software and system integration issues to minimize equipment downtime and maintain operational continuity.
• Perform routine preventive and corrective maintenance activities including equipment upgrades modifications and validation support.
• Execute installation testing and validation activities to verify equipment performance accuracy reliability and laboratory stability.
• Coordinate issue triage with end users vendors and external service providers while maintaining accurate equipment records maintenance logs and validation documentation.
• Train end users on laboratory automation systems and contribute to process improvements operational initiatives and innovations that enhance laboratory efficiency.

Required Skills Experience and Education

• Bachelors degree in engineering scientific discipline or a related field.
• 3 years of relevant experience with automated laboratory instruments and integrated automation systems
• Experience troubleshooting and developing custom scripts for Hamilton STAR/VANTAGE SPT Labtech firefly and other liquid handling instruments.
• Experience troubleshooting and writing protocols for Hamilton Venus and HighRes Bio Cellario schedulers.
• Experience with laboratory instrumentation and automation systems.
• Strong analytical skills collaboration documentation and communication skills.
• Must be able to prioritize and work well under pressure
• Proficiency in programming languages such as HSL VBScript JavaScript Python C or R.

Preferred Skills

• Knowledge of cell line development FACS or NGS workflows including routine cell line maintenance and expansion stem cell differentiation genotyping and high-throughput screening.
• Experience with Agilent VWorks Beckman Coulter Tempo/Echo and Formulatrix Cellmatic/Stack schedulers is a plus.

What Colossal Offers Full-Time Employees:

• Medical dental and vision coverage
• Excellent paid time off and company holidays so you can rest and recharge
• Flexible spending accounts (FSA)
• Company matched 401k retirement plan
• Paid parental leave at 100% salary for up to 12 weeks
• Education reimbursement
• An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed colorful passionate intelligent collaborative creative experienced scientific and world-class. That sounds like a lot to fit into one building. Thats why we are spread out in several locations that include laboratories test facilities academic institutions libraries and offices.

Through it all however we maintain a culture of positivity hope happiness and belief that were doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.

Colossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories inand 2026:

• #1 on the 50 Best Startups to Work For in Dallas in 2023!
• 100 Best Midsize Places to Work in Dallas in 2024 & 2025
• 100 Best Places to Work in Dallas TX (All Size Employers) inand 2026.

Built In 2026 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO most loved workplaces for LGBTQ most loved workplaces for women and most loved workplaces for young professionals.

Newsweeks Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweeks 2024 Most Loved Workplaces!