Director, US Commercial Enablement

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) Pompe disease and multiple DMD mutations. At Dyne we are on a mission to deliver functional improvement for individuals families and communities. Learn more at and follow us onXLinkedInandFacebook.

Role Summary

The Director US Commercial Enablement drives strategic commercial enablement initiatives and builds foundational tools processes and capabilities to support business growth and launch readiness. The Directorestablishesandoptimizesfield enablement infrastructure including incentive compensation CRM platforms and business intelligence tools while ensuring alignment across cross-functional stakeholders. This role enhances field effectiveness builds scalable processes and promotes operational excellence with a patient-first mindset.

Thisposition is basedinWalthamMA

Primary Responsibilities Include:

Incentive Compensation and Performance Programs

• Leads planning design and administration of incentive compensation and bonus programs across commercial medical and patient services teams
• Develops plan design models manages payouts and delivers monthly and quarterly reporting
• Maintains plan documentation tracking systems and performance monitoring processes
• Conducts regular performance reviews with stakeholders tooptimizeprogram effectiveness
• Partners with field teams to build account planning tools
• Leads recognition programs including Circle of Excellence and associated planning

Commercial Systems Tools and Analytics

• Serves as commercial business owner for CRM platforms (e.g. Veeva) translating field needs into system enhancements
• Partners with IT and stakeholders to implement andoptimizeCRM and data solutions
• Owns business intelligence reporting tools and ensures data accuracy through quality control processes
• Supports reporting platforms across market access and patient services
• Optimizesfield enablement tools and materials to improve productivity and effectiveness

Field Operations and Infrastructure

• Designs and implements fleet program aligned with business needs and industry benchmarks
• Maintains and updates fleet policies in collaboration with Compliance HR Finance and Field Leadership
• Builds scalable processes to support field teams and commercial operations

Cross-Functional Planning and Execution

• Leads coordination of national regional and headquarters meetings in partnership with Marketing and Commercial teams
• Drives cross-functional planning across Sales Marketing Market Access Advanced Analytics Patient Services Finance and IT
• Ensures alignment and readiness to support commercial launch and execution
• Strengthens collaboration and communication across teams

Education and Skills Requirements:

• Bachelors degree; advanced degree preferred
• 12 years of experience in biotech pharmaceutical or life sciences industry including field sales sales leadership field operations or consulting experience supporting commercial organizations
• Demonstrated experience supporting or leading launch readiness ideally in rare disease neuromuscular neurodegenerativeor neurodevelopmental therapies
• Strong leadership and project management experience including managing vendors and scaling commercial infrastructure
• Strategic mindset with ability to execute and deliver results
• Experience with commercial technology platforms and data environments (e.g. CRM BI tools Snowflake Boomi SP/SIP HUB data)
• Strong analytical and problem-solving skills
• Excellent written and verbal communication skills including ability to present to senior leadership
• Demonstrated ability to collaborate effectively across cross-functional stakeholders

#LI-Onsite

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education experience job-related knowledge and demonstrated skills.

The statements contained herein reflect general details as necessary to describe the principles functions for this job the level of knowledge and skill typically required and the scope of responsibility but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned including work in other functional areas to cover absences or relief to equalize peak work periods or otherwise balance workload.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age color disability gender national origin race religion sexual orientation veteran status or any classification protected by federal state or local law.