Director, Translational Medicine Clinical Lead-Immunology

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Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Clinical Development & Research MD

Job Category:

Scientific/Technology

All Job Posting Locations:

Cambridge Massachusetts United States of America San Diego California United States of America Spring House Pennsylvania United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at Immunology

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Director Translational Medicine Clinical Lead Translational Science & Medicine to be in Spring House PA La Jolla CA or Cambridge MA.

The Director Translational Medicine (TM) will be a program and experimental medicine leader in the Immunology Translational Science and Medicine (TSM) this position the Director TM will decisively contribute to accelerating the Immunology pipeline from portfolio entry to Proof-of-Concept (PoC).

The Director TM will function as a clinical lead/study responsible physician on early development programs and trials. They will contribute to creating translational plans for programs that are aligned with overall TA strategy and with relevant disease area and/or pathway strategies. They will be empowered to lead a cross-functional clinical trial team to deliver on the trials major execution milestones within governance-approved timeline and budget commitments. This responsibility extends end to end for clinical trials: from initial protocol design to continued monitoring and problem solving on trial execution to the analysis interpretation and communication of study results. This role will partner with Translational Sciences and deep engagement with investigators and external experts is this leadership role they will be supported by the senior leaders within the Translational Science and Medicine function including the relevant disease area leaders (both in clinical development and biomarker science) and a clinical study responsible scientist. The span of studies in scope are phase 1 (including focused experimental medicine studies) through Proof of Concept.

Within TM the Director will be part of a Translational Medicine Program Lead group which has primary responsibility within TSM for creating and implementing innovative translational plans for portfolio assets. TSM is a group within the Immunology Therapeutic Area consisting of a Translational Medicine and Translational Science (TS). TM has combined expertise in the clinical study of immunologic disease immunologic pathways and in early clinical trial design and execution. TS has expertise in biomarker development disease biology research and in the application of immunology and data science technologies to support drug development. Organizationally TSM serves as a pivotalbridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. This position will play a dual role contributing both scientific and clinical development expertise to TSM projects.

Responsibilities are as follows:

• Design and execute program translational strategies integrating both disease and pathway approaches.
• Design and execute early clinical trials through PoC including experimental medicine studies.
• Lead a cross-functional trial team to deliver on study milestones and commitments.
• Collaborate with translational science on the development and implementation of clinical biomarker and patient segmentation strategies.
• Support experimental medicine studies.
• Support Business Development including due diligence activities.
• Represent TM on early development teams.
• Represent TM for project teams when presenting to portfolio project and governance meetings.
• Lead or participate in cross-functional working groups such as scientific and safety review boards.
• Identify and collaborate with academic translational sites to optimize the translational strategy and plans for programs.
• Prepare and/or direct the preparation and review of protocols clinical study reports and translational medicine sections of Translational plans IBs INDs abstracts manuscripts and technical reports.
• Responsible for presentation of results and updates of projects at department project corporate and scientific meetings.

Qualifications:

• MD or MD/PhD degree required.
• Minimum of 3 years of industry and/or translational research experience required.
• Demonstrated supervisory and/or leadership experience with clinical and/or research teams is required.
• Training in Immunology and early clinical development trials is strongly preferred.
• Experience with innovative immune cell-based or biologic therapies is preferred.
• Experience in Oncology CAR-T and T cell engager therapies is not required but an area of interest.
• Strong track record in publications is preferred.
• Willingness and ability to travel including trans-Atlantic travel (up to 10%) is required.
• Location is Spring House PA Cambridge MA or La Jolla CA.

Subject to the terms of their respective plans employees are eligible to participate in the Companys consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Companys long-term incentive program.

Subject to the terms of their respective policies and date of hire employees are eligible for the following time off benefits:

• Vacation 120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado 48 hours per calendar year; for employees who reside in the State of Washington 56 hours per calendar year
• Holiday pay including Floating Holidays 13 days per calendar year
• Work Personal and Family Time - up to 40 hours per calendar year
• Parental Leave 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave 80 hours in a 52-week rolling period10 days
• Volunteer Leave 32 hours per calendar year
• Military Spouse Time-Off 80 hours per calendar year

The anticipated base pay range for this position is: $199000 - $398000

For additional general information on Company benefits please go to: - & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Required Skills:

Early Phase Clinical Trials Experimental Research Immunology Research Translational Medicine

Preferred Skills:

Business Savvy Clinical Research and Regulations Clinical Trials Collaboration Consulting Data Management and Informatics Design Mindset Drug Discovery Development Industry Analysis Innovation Market Research Regulatory Affairs Management Research Ethics Scientific Evaluation Scientific Research Stakeholder Management Strategic Analysis

The anticipated base pay range for this position is :

$199000.00 - $343850.00

Additional Description for Pay Transparency: