Ph.D. with an M.Pharm. in Pharmacognosy and over 7 years of multidisciplinary experience in drug discovery, pharmacology, toxicology, molecular biology, computational biology, and formulation development. Currently worki…
Ph.D. with an M.Pharm. in Pharmacognosy and over 7 years of multidisciplinary experience in drug discovery, pharmacology, toxicology, molecular biology, computational biology, and formulation development. Currently working as a Project Research Scientist at ICMR-NITM, Belagavi, with expertise in in vitro and in vivo efficacy studies. Previous work at CSIR-IICT involved the isolation, characterization, and biological evaluation of anticancer compounds, along with natural-product and synthetic-compound screening. Research experience spans ICMR-NITM, DBT-NIAB, CSIR-IICT, and CSIR-CIMAP. Author of 10+ peer-reviewed publications and inventor of a granted Indian patent, with strong capabilities in lead identification, scientific documentation, interdisciplinary project execution, and the translation of promising candidates toward preclinical development.
<p>Lead scientific coordination and execution of an ICMR-funded translational project involving discovery and preclinical evaluation of bioactive compounds and formulations.<br>
Design and conduct in vitro and in vivo efficacy studies of natural products, synthetic compounds, semisynthetic derivatives and nano-formulations; perform pharmacological and toxicological evaluation for lead prioritization.<br>
Standardize experimental workflows, analyze data, prepare technical reports/manuscripts/patent documentation, and mentor research personnel in laboratory methods and research documentation.</p>
<p>Investigated plant-derived and synthetic bioactive compounds using integrated biochemical, cellular, experimental and computational approaches.<br>
Performed bioactivity-guided screening, analytical characterization and in vitro/in vivo evaluation; applied protein modelling, docking, molecular dynamics and proteomics to investigate molecular targets and mechanisms.<br>
Generated peer-reviewed publications and intellectual property from translational research on bioactive compounds and formulations.</p>
<p>Conducted cell-based and biochemical screening of medicinal-plant extracts, natural compounds and synthetic compounds, including activity against Theileria annulata-infected bovine leucocytes and Rhipicephalus microplus.<br>
Determined IC50 values, investigated mechanisms of action, and used virtual screening, docking, MD, MM/GBSA and DFT to support lead identification.<br>
Contributed to formulation development, in vivo efficacy studies, statistical analysis and publication of research findings.</p>
<p>Performed HPLC/HPTLC-based quality evaluation and participated in in vitro and in vivo toxicity assessment of herbal formulations.</p>
<p>Isolated, characterized and biologically evaluated anticancer bioactive compounds from Lantana camara roots using chromatographic and bioassay approaches.</p>
<p>Performed physicochemical and analytical testing of pharmaceutical intermediates and maintained quality documentation.</p>
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