Bassam Yassen

Bassam Yassen

Computational biologist and data analyst
UAE
English, Arabic

About Me

Computational biologist and data analyst with a strong foundation in cell and molecular biology, spatial transcriptomics, and machine learning. Skilled in designing and executing end-to-end bioinformatics pipelines, gene…

Experience

Graduate Research Assistant — Spatial Transcriptomics

Khalifa University
Jan 2025 - Present · 1 year 9 months

<p>Designed and built end-to-end spatial transcriptomics analysis pipelines for UPEC bladder infection models using Seurat, Squidpy, and custom Python workflows<br>
Performed systematic comparison of TLR4-functional vs. TLR4-mutant mouse strains (C57BL/6 & CBA) to identify mechanisms underlying differences in bacterial clearance<br>
Constructed and interrogated gene regulatory networks (GRNs) using SCENIC+ and co-expression approaches to identify key transcription factor regulons<br>
Integrated scRNA-seq and spatial transcriptomics modalities to resolve cell-type-specific transcriptional programs at tissue-level resolution<br>
Deployed computational pipelines on HPC cluster via SLURM for large-scale parallelized processing of multi-sample experiments<br>
Produced publication-quality visualizations: spatial feature plots, UMAP embeddings, pathway enrichment charts, and GRN network diagrams</p>

Medical & Research Development Intern

Department of Health, Abu Dhabi · Abu Dhabi
Jun 2023 - Aug 2023 · 2 months

<p>Conducted structured quantitative data analysis to support evidence-based public health strategy recommendations<br>
Coordinated documentation and reporting for multi-disciplinary research projects, ensuring compliance with ethical and regulatory standards<br>
Contributed to data-driven reports informing health policy initiatives across Abu Dhabi health sector</p>

Research Assistant (Part-Time)

SaniService LLC
Jan 2022 - Jan 2023 · 1 year

<p>Conducted applied research on sanitation technologies, analysing performance data and generating detailed technical reports<br>
Developed data collection protocols and statistical analyses to evaluate product efficacy and performance benchmarks</p>

Skills

Python pandas NumPy scikit-learn Scanpy Squidpy Biopython Random Forest XGBoost Neural Networks TensorFlow Keras Seurat DESeq2 edgeR Limma ggplot2 Bioconductor Bayesian networks hypothesis testing multivariate analysis STARsolo Space Ranger STAR HISAT2 BWA GATK SAMtools Cell Ranger Seurat v5 DoubletFinder Plotly matplotlib seaborn Tableau SCENIC+ GENIE3 ARACNE HPC SLURM Linux Ubuntu Bash scripting workflow automation Git GitHub Jupyter Notebook R Markdown GSEA clusterProfiler
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