Senior Scientist – Digital Discovery AI-assisted Antibody Discovery & Data

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer heart disease inflammatory conditions rare diseases and obesity and obesity-related conditions. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Scientist Digital Discovery: AI-assisted Antibody Discovery & Data

What you will do

Lets do this. Lets change the this vital role you will

join the BioFoundry team within ImmunoEngineering. This role sits at the intersection of computational design in vivo antibody discovery and data generation enabling a closed-loop designmaketestlearn ecosystem for next-generation therapeutics.

AI-Guided Discovery & Experimental Translation

- Translate AI/ML-generated antibody designs (including zero-shot approaches) into experimentally testable strategies

- Design and execute workflows to express screen and characterize AI-derived antibodies

- Partner closely with computational and ML teams to refine hypotheses and improve design quality

Integrated Antibody Discovery

- Contribute to traditional antibody discovery workflows including in vivo / immunization-based platforms

- Apply comparative approaches to evaluate AI-designed vs. conventionally derived antibodies

- Help define best practices for integrating next-generation and established discovery paradigms

High-Throughput Data Generation & Structuring

- Develop and implement pipelines for systematic data capture curation and sharing

- Generate high-quality sequencefunction datasets to support model training and benchmarking

- Ensure experimental outputs are structured standardized and ML-ready

BioFoundry & Automation Integration

- Work with automation and platform teams to enable scalable high-throughput validation workflows

- Contribute to the development of a BioFoundry-enabled discovery engine

- Help define experimental designs that maximize throughput reproducibility and data value

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The professional we seek is a Scientist with these qualifications.

Basic Qualifications

- PhD in Biology Immunology Immunoengineering Biochemistry Bioengineering or related field

OR Masters degree 3 years of relevant experience

OR Bachelors degree 5 years of relevant experience

Preferred Qualifications

- Experience in antibody discovery and engineering including display technologies and/or in vivo platforms

- Hands-on experience with protein expression screening and characterization workflows

- Familiarity with high-throughput or automated experimental systems

- Exposure to computationally guided or AI-enabled discovery approaches

- Experience working with structured biological data databases or LIMS systems

- Demonstrated ability to work cross-functionally with computational data science or engineering teams

- Strong scientific communication and problem-solving skills

What you can expect from us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth. Click HERE for more details.

The base salary for this position is $115503 - $156269 CAD.

In addition to the base salary Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.

Apply now and make a lasting impact with the Amgen team.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range