Senior Director, Transformation Engineering Commercial AIA
New York City, NY - USA
Job Summary
Role Overview
The Senior Director Transformation Engineering is a senior technical leader responsible for rethinking how the enterprise operates in an AI-native world. This role goes beyond delivering technology it reimagines workflows organizational design and the operating model itself with a focus on identifying the most AI-native ways to enable change at scale.
This leader will drive strategic technology approaches that anticipate how applied engineers business teams and AI agents will work together differently in the future. They will partner across Digital and US Commercial functions to challenge legacy assumptions design new ways of working and translate AI capability into measurable operational impact.
Key Responsibilities
Reimagine Delivery
- Lead end-to-end rethinking of delivery and workflows identifying where AI-native approaches can replace augment or eliminate existing processes.
- Partner with senior leaders to surface high-impact transformation opportunities and translate them into actionable engineering roadmaps.
- Challenge legacy assumptions about how work gets done and develop a clear point of view on what an AI-native operating model looks like.
Drive AI-Native Strategy and Architecture
- Define and execute the strategic technology approach for embedding AI agents automation and intelligent workflows into core operations.
- Set architectural direction for how applied engineering teams build deploy and scale AI-native products and tooling.
- Evaluate emerging AI capabilities and translate them into pragmatic enterprise-grade solutions that deliver measurable outcomes.
Build and Lead the Future of Applied Engineering
- Shape how future applied engineers work including team design tooling ways of working and the human-agent collaboration model.
- Recruit develop and lead a high-performing team of engineers and technical leaders focused on transformation initiatives.
- Establish standards frameworks and best practices that scale AI-native engineering across the organization.
Deliver Strategic Impact
- Own outcomes for a portfolio of high-priority transformation initiatives with clear KPIs tied to efficiency quality revenue and experience.
- Communicate progress tradeoffs and recommendations to executive leadership and the board where appropriate.
- Build durable cross-functional partnerships with Product Data Commercial and Operations leaders.
Qualifications
Required
- 12 years of progressive experience in engineering technology or transformation leadership roles including significant time leading senior technical teams.
- Bachelors Degree required
- Demonstrated track record of leading large-scale transformation programs that delivered measurable business impact.
- Deep current expertise in AI/ML including hands-on understanding of agentic systems LLM-based workflows and AI-native product development.
- Strong systems thinking able to move fluidly between operating model design architecture and execution.
- Executive-level communication skills including the ability to influence senior business leaders and translate technical concepts into business outcomes.
- Experience building and leading high-performing engineering teams in a matrixed environment.
Preferred
- Prior experience as a senior engineering or transformation leader at a top technology company consultancy or large enterprise.
- Background that combines strategy product and engineering with credibility across all three.
- Experience deploying AI agents or AI-native workflows in regulated or enterprise environments.
- Advanced degree in Computer Science Engineering or a related technical field.
Last Day to apply: May 13 2026
Location: Selected colleague much be onsite 2.5x weekly.
The annual base salary for this position ranges from $230900.00 to $384800.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN O-1 H-1B etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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