Senior Director, Head of Translational AI Science (CVRM)

Gothenburg Sweden

Introduction
At AstraZeneca we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial thinking big and working together to make the impossible a reality.

Were building a connected end-to-end Enterprise AI engine - uniting data foundations AI technology process reinvention and business-facing AI to accelerate results across the whole value chain. Success depends on being exceptional connectors: youll actively leverage existing capabilities celebrate and promote reuse export breakthrough ideas across geographies and functions and obsess over scaling impact rather than building in isolation. If you thrive in high-collaboration environments where your role is to turn complex cross-functional problems into reusable enterprise-wide capabilities - and where the measure of success is adoption and scale not just innovation - youll have the platform (and sponsorship) to make it real.

The role
The Head of Translational AI Science (CVRM) leads a small high-impact team focused on advancing mechanistic understanding of cardiovascular renal and metabolic diseases. The role operates at the intersection of biology medicine and artificial intelligence uncovering mechanism of disease (MoD) mechanism of action (MoA) and mechanism of resistance (MoR) with modern AI approaches in a way that significantly enhances and accelerates translational decision-making.

You will work side-by-side with senior leaders in Translational Medicine deeply understanding needs at all levels creating opportunities influencing priorities and balancing trade-offs. Through rigorous prioritisation you will develop and guide innovative resource-aware strategies that combine cutting-edge AI techniques with domain expertise to create value tightly aligned to the therapy area portfolio.

You will manage a team of Translational AI Scientists and work in close partnership with the AI Center of Excellence to translate scientific questions into scalable AI solutions. Success will come from inclusive collaboration scientific leadership and an aptitude for people development.
You will bring hands-on understanding of current and emerging frontier AI capabilities to guide data strategy and implementation model selection and development ensuring biological insight is embedded into foundation models causal frameworks and simulation approaches. You will collaborate across therapy areas to ensure outputs are aligned valid scientifically robust and actionable for R&D.

Why CVRM at AstraZeneca
Cardiovascular renal and metabolic diseases remain among the leading causes of mortality globally representing a significant unmet medical need. At AstraZeneca CVRM is a core strategic priority with a strong portfolio deep scientific expertise and access to rich multimodal data.
This creates a unique environment to apply AI-first approaches to uncover new biological insights accelerate decision-making and ultimately deliver better outcomes for patients at scale.

Essential for the role
Expertise in translational science and mechanistic thinking (MoD MoA MoR) ideally within CVRM
Demonstrated experience applying modern AI in biomedical or translational settings (e.g. foundation models causal inference multimodal learning)
Strong quantitative background in mathematical statistical or computational methods
Ability to translate scientific questions into implementable AI approaches
Experience leading teams delivering AI-driven capabilities across multiple projects or portfolios
Track record of delivering impact within complex R&D environments
Proven ability to deliver at pace balancing scientific rigor with speed and impact
Strong communication skills and ability to influence senior stakeholders

Office Working Requirements
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Apply now to lead at the frontier of AI and translational science and help shape how AstraZeneca transforms drug development through Enterprise AI.

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