Sr Program Manager PMO

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

As guided by Our Credo Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson we respect the diversity and dignity of our employees and recognize their merit.

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Fueled by innovation at the intersection of biology and technology were developing the next generation of smarter less invasive more personalized treatments.

Are you passionate about improving and expanding the possibilities of Cardiovascular Ready to join a team thats reimagining how we heal Our Cardiovascular team develops leading solutions for heart recovery electrophysiology and stroke. You will join a proud heritage of continually elevating standards of care for stroke heart failure and atrial fibrillation (AFib) patients.

Your unique talents will help patients on their journey to wellness. Learn more at are searching for the best talent for a Senior Program Manager-PMO to support our Electrophysiology business. This role will work a Flex/Hybrid schedule with 2-3 days per week onsite in our Irvine CA office.

The Senior Program Manager leads end-to-end program delivery across the product portfolio within the PMO organization owning the integrated plan budget risk framework and governance to ensure cohesive value-driven outcomes. This leader aligns multiple related projects manages cross-functional matrixed teams (product engineering operations and regulatory/compliance) and drives RAID KPIs and stage-gate compliance per PMO standards. The role facilitates prioritization escalates decisions as needed and partners with stakeholders to realize measurable business value while ensuring regulatory readiness in a MedTech-like environment. The Program Manager also leads change management and adoption efforts providing clear program reporting to executives and balances rigor with flexibility to sustain delivery momentum.

DUTIES & RESPONSIBILITIES

Under (e.g. limited supervision general direction etc.) and in accordance with all applicable federal state and local laws/regulations and Corporate Johnson & Johnson procedures and guidelines this position:

• Serve as the End-to-End Program Head for the product delivery area establishing and enforcing governance success criteria and decision rights.
• Own RAID management (Risks Assumptions Issues Dependencies) and ensure alignment with PMO standards and defined KPIs.
• Develop own and maintain the integrated program plan (scope schedule cost resources deliverables milestones timelines) with baseline management.
• Implement and monitor change control baselines and escalation paths; ensure documentation supports stage-gate requirements and regulatory expectations.
• Ensure multiple related projects align to deliver one cohesive value-driven outcome; optimize interdependencies and sequencing to maximize program value and strategic impact.
• Define and track benefits realization metrics; translate program outcomes into measurable business value.
• Develop own and monitor the overall program budget; provide guidance for resource allocation and forecasts; collaborate with finance for fiscal health and cost controls.
• Own program-level risk management framework; maintain the program risk register; drive proactive mitigation issue resolution and contingency planning.
• Manage dependencies and assumptions across projects; ensure timely escalation and resolution.
• Lead cross-functional engagements and manage program core-teams (e.g. product engineering operations regulatory/compliance); cultivate collaboration accountability and clear decision rights.
• Demonstrate strong stakeholder influence and alignment across functional boundaries.
• Own the program reporting process and status updates; deliver executive dashboards and concise governance packs highlighting risks decisions and impacts.
• Establish and monitor KPIs aligned with PMO standards; provide actionable insights to sponsors and leadership.
• Drive program deliverables to meet stage-gate criteria; validate quality gates acceptance criteria and regulatory or governance standards prior to progression.
• Ensure documentation and processes meet regulatory requirements where applicable.
• Facilitate prioritization among initiatives within the program; support leadership in assessing trade-offs among scope schedule cost and business value.
• Lead change management activities to drive adoption of new processes or systems; plan user readiness training and sustainment strategies.
• Align program activities with applicable quality systems regulatory requirements and industry standards; ensure audit readiness and evidence of compliance.
• Promote best practices standards and continuous improvement; maintain alignment with PMO methodologies and governance to drive maturity and consistency.
• Manage vendor relationships contracts performance and influencer risk to support program objectives.
• Leverage organizational tools (e.g. MS Project Smartsheet Clarity Jira etc.) for planning tracking and reporting; ensure tool usage supports transparency and governance.
• Demonstrate business acumen with an understanding of strategy financials and value realization; translate technical delivery into business outcomes.

QUALIFICATIONS:

• Bachelors degree in engineering or science discipline required; MBA or equivalent preferred.
• Minimum of 8 years in the role of project/program manager in a related field.
• Proven track record of delivering multi-project initiatives with cross-functional teams.
• Experience in governance-driven environments (PMO portfolio management).
• Results-oriented organized and analytical; balances rigor with practical ability.
• Strong communicator and influencer; fosters collaboration and transparency in delivery.
• Comfortable with operational trade-offs escalation management and timely decision making.
• Demonstrated experience leading matrixed or virtual teams.
• Proactive collaborative leader who promotes a culture of openness accountability and continuous learning.

REQUIRED KNOWLEDGE SKILLS ABILITIES and CERTIFICATIONS/LICENSES:

• PMP PgMP or MSP certification are desirable.
• Agile/Scrum or Lean Six Sigma certification is a plus.

• In-depth knowledge of MedTech industry medical device regulations and external standards.
• Must successfully complete Company training programs.
• Advanced computer skills and the ability to multitask without direct oversight of manager.
• Travel: 25% expected travel for domestic international or both

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via Internal employees contact AskGS to be directed to your accommodation resource.

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Manager