Principal Scientist – NGSGenomics and Bioinformatics

Work Schedule

Environmental Conditions

Job Description

This is a fully onsite role basedinour bioanalytical laboratory in Richmond VA. We welcome applicants from all locations within the note that relocation assistance is not provided for this position and any relocation costs will be the responsibility of the candidate.

Must be legally authorized to work in the United States withoutsponsorship.

Must be able to pass a comprehensive background check whichincludes a drug screening.

At Thermo Fisher Scientific youll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research development and delivery of life-changing therapies. With clinical trials conducted in 100 countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio our work spans laboratory digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on now and in the future.

Our PPD Laboratory Services team has a direct impact on improving patient health through the expertise of scientists industry thought-leaders and therapeutic experts. As the world leader in serving science our laboratory professionals bring their commitment to accuracy and quality to deliver groundbreaking innovations.

Discover Impactful Work:

Discover Impactful Work: We are seeking a Principal Scientist to lead the strategy design and implementation of our NGS sequencing platforms. This role defines the next phase of our laboratorys molecular innovationcombining sequencing proteomics and spatial transcriptomics to deliver integrated multi-omics solutions.

A Day in the Life:

• Oversee setup qualification and validation of the Ultima and/or Illumina NGS system
• Lead evaluation and implementation of genomics and proteomics technologies (NextGen Sequencing (WGS RNASeq targeted sequencing) spatial sequencing (10x Genomics Chromium Visium Xenium) O-Link HT NuLISA)
• Define and execute the sequencing strategy for the lab aligning with organizational and client objectives
• Mentor scientists and analysts in NGS workflows QC and data interpretation including bioinformatics support
• Partner with automation bioinformatics and proteomics teams for multi-omics integration
• Represent the lab in vendor partnerships conferences and technical collaborations

Keys to Success:

• Bachelors degree or equivalent and relevant formal academic / vocational qualification
• Previous experience that provides the knowledge skills and abilities to perform the job (comparable to 12 years) or equivalent combination of education training and experience.
• OR Masters degree and previous experience that provides the knowledge skills and abilities to perform the job (comparable 10 year)
• OR PhD and previous experience that provides the knowledge skills and abilities to perform the job (comparable 8 year)

In some cases an equivalency consisting of a combination of appropriate education training and/or directly related experience will be considered sufficient for an individual to meet the requirements of the role.

Knowledge Skills and Abilities:

• Demonstrated leadership in launching or managing NGS and spatial sequencing platforms and analysis
• Ultima and/or Illumina NGS - MUST HAVE
• Proven track record of cross-functional scientific leadership and technical innovation
• Expert knowledge of sequencing chemistry data QC and assay validation data analysis/bioinformatics
• Experience integrating sequencing with proteomics or other omics technologies
• Strong communication and external collaboration skills
• Strategic mindset with ability to identify and implement new technologies
• Demonstrated success mentoring staff and building scientific teams

Working Conditions and Environment:
Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment.

• Occasional drives to site locations occasional domestic travel
• Exposure to biological fluids with potential exposure to infectious organisms
• Rare exposure to skin and lung irritants radiation toxic materials and hazardous waste
• Personal protective equipment required such as protective eyewear garments and gloves
• Exposure to fluctuating and/or extreme temperatures on rare occasions