Postdoctoral Fellow in Allergy and Immunology
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Job Location:
Boston, NH - USA
Monthly Salary:
Not Disclosed
Posted on:
2 days ago
Vacancies:
1 Vacancy
Job Summary
Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The Patil laboratory in the in the Center for Immunology and Inflammatory Diseases (CIID) at Massachusetts General Hospital and Harvard Medical School is seeking a highly motivated postdoctoral fellow to study allergen-specific B cells in the development and treatment of allergic diseases.My laboratory seeks to understand how allergies develop and how they can be effectively treated by understanding the role of antibodies in allergy and tolerance. Our translational research approach leverages the application of cutting edge sample sparing techniques to understand clinical manifestations of disease. To that end we have pioneered the application of fluorescent multimers to identify rare allergen-specific B cells combined with single cell B cell receptor sequencing to structurally characterize of antibodies and their antigenic targets on a subatomic level. Our work has led to the identification of neutralizing antibodies and their role in sustained responses after oral immunotherapy as well as the identification of convergent or public antibodies. From this work we have a clearer insight into antibodies from individuals but also on a population level.
We are seeking a highly motivated PhD MD/PhD or MD scientist with a background in molecular biology with an interest in bioinformatics to lead translational research in food allergy. and translating these discoveries into new therapeutic order to understand the role of allergen-specific B cells in the development of food allergies and treatment the candidate will engage in cutting-edge technologies unifying allergen-specific B cell studies with transcriptomics proteomics and functional assays to discover novel therapies for food allergy. Individual projects will be tailored to the candidates background and interests.
Qualifications
The ideal candidate has a strong background and experimental immune phenotyping mammalian cell culture and a broad range of molecular and cellular biology techniques including genomics approaches. A strong ability to work independently and in a team troubleshoot experimental challenges and maintain attention to detail is valued as are analytical organizational and communication skills. A documented track record of significant prior scientific achievement in the field of immunology is encouraged.
Applicants should submit 1. A cover letter describing their previous scientific accomplishments and interests and career goals 2. Their C.V. and 3. Contact information for three references via e-mail to Sarita U. Patil MD at
Please do not apply through this link.
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Patients at Mass General have access to a vast network of physicians, nearly all of whom are Harvard Medical School faculty and many of whom are leaders within their fields.
