PhD Student

Africa Health Research Institute

Job Location:

Durban - South Africa

Monthly Salary: Not Disclosed

Posted on: 9 days ago

Vacancies: 1 Vacancy

Job Summary

Description:

The Ndhlovu lab is seeking to appoint a PhD student to join our HIV cure team focused on understanding how HIV-specific CD8 T cells interact with the persistent viral reservoir in human lymphoid tissues. This project investigates why virus-specific immune responses fail to eliminate HIV from immune-privileged sites such as lymph node B cell follicles and gut-associated lymphoid tissue (GALT).

Overview of Duties:

Using cutting-edge spatial transcriptomics and single-cell technologies the trainee will lead studies to:

Define the phenotypic and functional characteristics of tissue-resident antigen-specific CD8 T cells; and Elucidate immune-regulatory mechanisms within lymphoid tissues that contribute to HIV persistence during suppressive antiretroviral therapy.

This position offers a unique opportunity to contribute to translational HIV cure research in a highly collaborative and interdisciplinary environment.

Learn more about the Ndhlovu lab please follow this link: and experience:

MSc in immunology virology or related field
Strong background in T cell biology HIV immunology or chronic viral infections
Hands-on experience with spatial transcriptomics multiplex imaging (e.g. CODEX MIBI) or single-cell RNA-seq
Flow cytometry experience
Skilled in high-dimensional data analysis (e.g. FlowJo R Python)
Proven publication record and excellent communication skills

We offer:

Access to cutting-edge platforms:GeoMX DSPLunaphore COMET 40-plex10x Genomics and high-parameter flow cytometry
A collaborative interdisciplinary team environment and global partnerships
Competitive stipend
Opportunities for career development conference attendance and international collaboration

How to apply:

Please complete an application form by clicking on the apply link above. You are expected to attach:

A cover letter outlining your fit and research interests
One to two-page CV
Two academic references
Academic records

Should you have any enquiries about the position please email with the subject line: Spatial and functional profiling of HIV-specific T cells in lymphoid reservoirs for cure-relevant insights.

Worker Type:

Contingent Worker

The application closing date:

21 Mar 2026

Please note that only shortlisted candidates will be contacted kindly consider your application as unsuccessful if you do not hear from us within 14 days of the application closing date.

Description: The Ndhlovu lab is seeking to appoint a PhD student to join our HIV cure team focused on understanding how HIV-specific CD8 T cells interact with the persistent viral reservoir in human lymphoid tissues. This project investigates why virus-specific immune responses fail to eliminate HIV...