Postdoctoral fellows in ubiquitin biology research

Bhogaraju group at EMBL Grenoble has several postdoc positions open to conduct fundamental and translational research into a class of understudied human ubiquitin ligases. Our group explores Melanoma-associated antigen (MAGE)-RING ubiquitin ligases (MRLs) some of which are highly oncogenic. We are looking for passionate and ambitious colleagues who are willing to make significant fundamental discoveries related to the medically relevant MRLs and their ubiquitination substrates.

Our recent work includes the discovery of a conserved ligase-binding cleft in MAGE proteins showcasing (Griffith-Jones et al. 2024). We also developed a proteomics-based ubiquitin ligase-substrate mapping method known as Ub-POD which is being widely used in the field (Mukhopadhyay et al. 2024). Bhogaraju group uses Proteomics cell biology and structural biology methods to study human ubiquitin ligases especially MRLs. See further information at lab webpage qualifications:

• A PhD in Biochemistry/Cell biology or related field
• At least one first author research article/preprint
• Strong understanding of quantitative proteomics and its applications
• Proficiency in common molecular biology and cell biology techniques
• Knowledge of Immunofluorescence microscopy

Preferred qualifications:

• Experience in protein purifications and protein biochemistry is a plus
• Basic understanding of protein structural biology and Protein structure analysis
• Experience in induced degradation modalities is a plus

Preferred personal attributes:

• Strong team player with willingness to collaborate
• Proactive in decision-making
• Critical thinker with strong problem-solving abilities

Contract length:2 years (with the possibility of extension)

Salary: Monthly stipend (first year): 3.64624 (after tax excl. pension & insurances) benefits

Professional development support

The EMBL Fellows Career Service provides support and guidance to predoctoral and postdoctoral fellows across all six EMBLs sites.

Working with a dedicated Careers Advisor this invaluable service will help you to take informed decisions about your career planning both in the short and longer term. Whether your main interest is pursuing a career path in academia exploring opportunities in industry or exploring an independent venture the EMBL Fellows Career Service with provide you with a portfolio of activities and resources to help you.

To find out more please visit - EMBL-fellows-career-service

Why join us

Enjoy lots of employee benefits:

• Financial incentives:Monthly family and child allowances generous stipend reviewed yearly pension scheme death benefit and unemployment insurances

• Flexible working arrangements including hybrid working patterns

• Private medical insurancefor you and your immediate family

• Generous time off:30 days annual leave per year in addition to public holidays

• Campus life:Free shuttle bus (Heidelberg) on-site library subsidised on-site cafeteria casual dress code extensive sports and social club activities (on campus and remotely)

• Family benefits: Kindergarten (Heidelberg) 10 days of child sick leave paid maternity & parental leave holiday clubs on campus and monthly family and child allowances
  

What else you need to know

• International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants.

• Diversity and inclusion: At EMBL we believe that diverse teams drive innovation and scientific excellence. We encourage applications from candidates of all genders identities nationalities and/or any other diverse backgrounds.

• Job location: All our fellowships are based on-site (for at least part of each week). If you are living overseas you will receive a generous relocation package to support you.

• EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here

• How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date.

Closing Date